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Sibenadet hydrochloride

Cat. No. M28582

All AbMole products are for research use only, cannot be used for human consumption.

Sibenadet hydrochloride Structure
Synonym:

AR-C68397AA

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Quality Control & Documentation
Biological Activity

Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.

Chemical Information
Molecular Weight 501.06
Formula C22H29ClN2O5S2
CAS Number 154189-24-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jonathan P Bradley, et al. J Pharm Sci. Probing intermolecular hydrogen bonding in sibenadet hydrochloride polymorphs by high-resolution (1) H double-quantum solid-state NMR spectroscopy

[2] Stephen Connolly, et al. Bioorg Med Chem Lett. Design-driven LO: the discovery of new ultra long acting dibasic β2-adrenoceptor agonists

[3] S D Cosgrove, et al. J Pharm Sci. Understanding the polymorphic behavior of sibenadet hydrochloride through detailed studies integrating structural and dynamical assessment

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Keywords: Sibenadet hydrochloride, AR-C68397AA supplier, Dopamine Receptor, inhibitors, activators

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