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Ecopipam hydrobromide

Cat. No. M29720

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Ecopipam hydrobromide Structure
Synonym:

SCH 39166 hydrobromide

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Quality Control & Documentation
Biological Activity

Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrobromide shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrobromide can be used for the research of schizophrenia and obesity.

Chemical Information
Molecular Weight 394.73
Formula C19H21BrClNO
CAS Number 2587360-22-1
Form Solid
Storage -20°C, dry, sealed
References

[1] Rebecca J Ralph, et al. J Pharmacol Exp Ther. Dopamine D1 and D2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague-Dawley rats to Swiss-Webster, 129X1/SvJ, C57BL/6J, and DBA/2J mice

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Keywords: Ecopipam hydrobromide, SCH 39166 hydrobromide supplier, Dopamine Receptor, inhibitors, activators

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