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PLpro inhibitor

Cat. No. M9641

All AbMole products are for research use only, cannot be used for human consumption.

PLpro inhibitor Structure
Size Price Availability Quantity
1mg USD 85  USD85 In stock
5mg USD 210  USD210 In stock
10mg USD 340  USD340 In stock
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Quality Control & Documentation
Biological Activity

PLpro inhibitor is a potent papain-like protease (PLpro) inhibitor with IC50 of 2.6 μM. PLpro inhibitor shows significant antiviral activity with EC50 values of 13.1 μM, without toxicity up to the highest concentration tested.

Chemical Information
Molecular Weight 346.42
Formula C22H22N2O2
CAS Number 1093070-14-4
Solubility (25°C) DMSO 10 mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brendan T Freitas, et al. ACS Infect Dis. Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease

[2] Kiira Ratia, et al. Proc Natl Acad Sci U S A. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

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Keywords: PLpro inhibitor supplier, Anti-infection, inhibitors, activators

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