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Phenothrin

Cat. No. M2937

All AbMole products are for research use only, cannot be used for human consumption.

Phenothrin Structure
Synonym:

Sumithrin

Size Price Availability Quantity
200mg USD 105  USD105 In stock
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Quality Control & Documentation
Biological Activity

Phenothrin, also called sumithrin, is a synthetic pyrethroid that kills adult fleas and ticks.

Customer Product Validations & Biological Datas
Source PLoS One (2015). Figure 1. Phenothrin
Method Insecticide Sensitivity
Cell Lines Honey Bee Stocks
Concentrations 0.5 ug/bee
Incubation Time 24 h
Results Phenothrin sensitivity significantly decreased by 1.7-, 1.8-, and 2.1-fold in 14-, 28-, and 42-dayold bees, respectively, compared to 3-day-old bees. The decrease in phenothrin sensitivity was significantly correlated with age
Protocol (for reference only)
Cell Experiment
Cell lines HepG2 cell
Preparation method The cells were exposed to increasing doses of phenothrin (20, 50, 100, 1000 μM) in the corresponding cell-culture medium. The stock solution and the dilution series (100 μM, 10 μM, 1 μM) were made in methanol. Aliquots of different concentrations of phenothrin solution or solvent control were added to the cell cultures and incubated for 1 h at 37°C. The methanol content in the cell culture fluid was 10% (v/v) for each treatment, the concentration found to be non-genotoxic and non-cytotoxic in our previous experiments (unpublished).
Concentrations 20, 50, 100, 1000 μM
Incubation time 1 h
Animal Experiment
Animal models Crj:CD(SD)IGS rats
Formulation
Dosages 0, 100, 300 or 1000 mg/kg/d
Administration oral gavage
Chemical Information
Molecular Weight 350.45
Formula C23H26O3
CAS Number 26002-80-2
Solubility (25°C) DMSO 10 mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Nagy K, et al. Mutat Res Genet Toxicol Environ Mutagen. Evaluation of the genotoxicity of the pyrethroid insecticide phenothrin.

[2] Yamada T, et al. Toxicology. Lack of estrogenic or (anti-)androgenic effects of d-phenothrin in the uterotrophic and Hershberger assays.

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Keywords: Phenothrin, Sumithrin supplier, Anti-infection, inhibitors, activators

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