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Paederoside

Cat. No. M4330
Paederoside Structure
Size Price Availability Quantity
5mg USD 150  USD150 In stock
10mg USD 250  USD250 In stock
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Quality Control & Documentation
Biological Activity

Paederoside is a monoterpene S-methyl thiocarbonate isolated from Paederia Pertomentosa. Paederoside showed high antitumor promotion and inhibited epstein-Barr virus activation.

Chemical Information
Molecular Weight 446.43
Formula C18H22O11S
CAS Number 20547-45-9
Form Solid
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Zhi-Jun Wu, et al. Analysis of iridoid glucosides from Paederia scandens using HPLC-ESI-MS/MS

[2] Xu Zou, et al. Sulfur-containing iridoid glucosides from Paederia scandens

[3] Yoshio Takeda, et al. An iridoid glucoside dimer and a non-glycosidic iridoid from the leaves of Lasianthus wallichii

[4] Dang Ngoc Quang, et al. Iridoid glucosides from roots of Vietnamese Paederia scandens

[5] H Inouye, et al. Studies on monoterpene glucosides. 8. Artefacts formed during extraction of asperuloside and paederoside

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