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Meclofenamic acid sodium hydrate

Cat. No. M30459

All AbMole products are for research use only, cannot be used for human consumption.

Meclofenamic acid sodium hydrate Structure
Synonym:

Meclofenamate sodium hydrate

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Quality Control & Documentation
Biological Activity

Meclofenamic acid (Meclofenamate) sodium hydrate is a non-steroidal anti-inflammatory agent. Meclofenamic acid sodium hydrate is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid sodium hydrate competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid sodium hydrate is a non-selective gap-junction blocker. Meclofenamic acid sodium hydrate inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.

Chemical Information
Molecular Weight 336.15
Formula C14H12Cl2NNaO3
CAS Number 67254-91-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] B S Kang, et al. Biol Pharm Bull. Inhibitory effects of anti-inflammatory drugs on interleukin-6 bioactivity

[2] A Hassid, et al. Proc Natl Acad Sci U S A. Prostaglandin synthesis in isolated rat kidney glomeruli

Related FTO Products
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FTO-IN-1 TFA is a fat mass and obesity-associated enzyme (FTO) inhibitor, with an IC50 of <1 μM.

Ethyl LipotF 

Ethyl LipotF is a selective FTO inhibitor that significant increases modified N6-methyladenosine (m6A) levels in HeLa cells in a concentration-dependent manner.

ZLD115

ZLD115 is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO).

Meclofenamic acid

Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.

FB23

FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

  Catalog
Abmole Inhibitor Catalog




Keywords: Meclofenamic acid sodium hydrate, Meclofenamate sodium hydrate supplier, FTO, inhibitors, activators

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