| Cat.No. | Name | Information |
|---|---|---|
| M9422 | FB23-2 | FB23-2 is a potent and selective FTO inhibitor with an IC50 of 2.6 μM, directly binds to FTO and selectively inhibit FTO's m6A demethylase activity. |
| M3998 | Rhein | Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb. |
| M25586 | FB23 | FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. |
| M11375 | Dac51 | Dac51 is an effective FTO inhibitor with an IC50 of 0.4 μM against FTO demethylation. |
| M2669 | Entacapone | Entacapone is an inhibitor of FTO demethylation with IC50 of 3.5 μM, Entacapone also inhibits catechol-O-methyltransferase (COMT) with IC50 of 151 nM. |
| M42400 | ZLD115 | ZLD115 is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO). |
| M30459 | Meclofenamic acid sodium hydrate | Meclofenamic acid sodium hydrate is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid sodium hydrate inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively. |
| M30422 | Meclofenamic acid | Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively. |
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