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FTO-IN-1 TFA is a fat mass and obesity-associated enzyme (FTO) inhibitor, with an IC50 of <1 μM.
Molecular Weight | 505.27 |
Formula | C20H17Cl2F3N4O4 |
CAS Number | 2797619-81-7 |
Form | Solid |
Solubility (25°C) | DMSO 50 mg/mL; |
Storage | 4°C, dry, sealed |
Related FTO Products |
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Ethyl LipotF
Ethyl LipotF is a selective FTO inhibitor that significant increases modified N6-methyladenosine (m6A) levels in HeLa cells in a concentration-dependent manner. |
ZLD115
ZLD115 is a FB23-derivated inhibitor of Fat Mass and Obesity-associated Protein (FTO). |
Meclofenamic acid sodium hydrate
Meclofenamic acid sodium hydrate is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid sodium hydrate inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively. |
Meclofenamic acid
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively. |
FB23
FB23 is a potent and selective FTO demethylase inhibitor with an IC50 of 60 nM. FB23 binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. |
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