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Lycorine

Cat. No. M14434

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Lycorine Structure
Size Price Availability Quantity
50mg USD 85  USD85 In stock
100mg USD 135  USD135 In stock
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Quality Control & Documentation
Biological Activity

Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases.

Chemical Information
Molecular Weight 287.31
CAS Number 476-28-8
Solubility (25°C) DMSO 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Na Li, et al. In Vitro Inhibition of Alphaviruses by Lycorine

[2] Shixue Zhao, et al. Antifungal effects of lycorine on Botrytis cinerea and possible mechanisms

[3] Strahil Berkov, et al. GC-MS of some lycorine-type Amaryllidaceae alkaloids

[4] Qing Liang, et al. Lycorine ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3 inflammasome activation and pyroptosis

[5] Mridul Roy, et al. Lycorine: A prospective natural lead for anticancer drug discovery

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Keywords: Lycorine supplier, FAS, inhibitors, activators

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