Free shipping on all orders over $ 500

Eicosapentaenoic acid ethyl ester

Cat. No. M20994

All AbMole products are for research use only, cannot be used for human consumption.

Eicosapentaenoic acid ethyl ester Structure
Synonym:

AMR101, EPA ethyl ester, Ethyl eicosapentaenoate

Size Price Availability
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels.

Chemical Information
Molecular Weight 330.5
Formula C22H34O2
CAS Number 86227-47-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] M John Chapman, et al. Pharmacol Ther. Reducing residual cardiovascular risk in Europe: Therapeutic implications of European medicines agency approval of icosapent ethyl/eicosapentaenoic acid

[2] Yawei Fu, et al. Mediators Inflamm. Associations among Dietary Omega-3 Polyunsaturated Fatty Acids, the Gut Microbiota, and Intestinal Immunity

[3] Klaus G Parhofer, et al. Dtsch Arztebl Int. The Diagnosis and Treatment of Hypertriglyceridemia

[4] Deepak L Bhatt, et al. N Engl J Med. Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia

[5] James Backes, et al. Lipids Health Dis. The clinical relevance of omega-3 fatty acids in the management of hypertriglyceridemia

Related FAS Products
GSK837149A 

GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer.

IPI-9119

IPI-9119 is an orally active, selective and irreversible Fatty Acid Synthase (FASN) inhibitor, with an IC50 of 0.3 nM.

FT113

FT113 is a potent inhibitor of fatty acid synthase(FASN) with ic50 of 213 nM.

PF429242 dihydrochloride

PF429242 dihydrochloride is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM.

Lycorine

Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant.

  Catalog
Abmole Inhibitor Catalog




Keywords: Eicosapentaenoic acid ethyl ester, AMR101, EPA ethyl ester, Ethyl eicosapentaenoate supplier, FAS, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.