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L-745870 trihydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 trihydrochloride shows weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and α-adrenoceptors.
| Molecular Weight | 436.21 |
| Formula | C18H22Cl4N4 |
| CAS Number | 866021-03-6 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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