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Ecopipam hydrochloride

Cat. No. M29005

All AbMole products are for research use only, cannot be used for human consumption.

Ecopipam hydrochloride Structure
Synonym:

SCH 39166 hydrochloride

Size Price Availability Quantity
10mg USD 190  USD190 In stock
25mg USD 380  USD380 In stock
50mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity.

Chemical Information
Molecular Weight 350.28
Formula C19H21Cl2NO
CAS Number 190133-94-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Hong Zheng, et al. Am J Physiol Regul Integr Comp Physiol. Attenuated dopaminergic tone in the paraventricular nucleus contributing to sympathoexcitation in rats with Type 2 diabetes

[2] Sandro Fenu, et al. Physiol Behav. Differential involvement of dopamine D1 receptors in morphine- and lithium-conditioned saccharin avoidance

[3] S Fenu, et al. J Neurosci. A role for dopamine D1 receptors of the nucleus accumbens shell in conditioned taste aversion learning

[4] E Acquas, et al. Eur J Pharmacol. Dopamine D(1) receptor-mediated control of striatal acetylcholine release by endogenous dopamine

[5] A M Alam, et al. Exp Brain Res. Bimodal effects of dopamine D2 receptor agonists on zero Mg(2+)-induced epileptiform activity in the rat cingulate cortex slice

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Keywords: Ecopipam hydrochloride, SCH 39166 hydrochloride supplier, Dopamine Receptor, inhibitors, activators

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