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Ch55

Cat. No. M14526

All AbMole products are for research use only, cannot be used for human consumption.

Ch55 Structure
Size Price Availability Quantity
5mg USD 120  USD120 In stock
10mg USD 175  USD175 In stock
25mg USD 350  USD350 In stock
50mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Ch55 is a potent synthetic retinoid. Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC50 of 200 nM. Ch55 can be used for cancer research.

Chemical Information
Molecular Weight 364.48
CAS Number 110368-33-7
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Anjuman Arif, et al. A Comparative Study for Assessing the Drought-Tolerance of Chickpea Under Varying Natural Growth Environments

[2] Erica Elisa Ferrandi, et al. Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries

[3] N Takahashi, et al. Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80

[4] Y Hashimoto, et al. Specific uptake of retinoids into human promyelocytic leukemia cells HL-60 by retinoid-specific binding protein: possibly the true retinoid receptor

[5] K Tamura, et al. Synthetic retinoids, retinobenzoic acids, Am80, Am580 and Ch55 regulate morphogenesis in chick limb bud

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Keywords: Ch55 supplier, RAR/RXR, inhibitors, activators

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