About 12 results found for searched term "Ch55" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11172 | Reslizumab | IL Receptor/Related |
| Sch 55700 | ||
| Reslizumab (Sch 55700) is a humanized monoclonal antibody targeting human interleukin 5 (IL-5) for the study of eosinophilic asthma. Reslizumab effectively blocks il-5 function. Reslizumab inhibited IL-5-dependent cell proliferation with an IC50 of about 91.1 pM. | ||
| M5400 | Alosetron Hydrochloride | 5-HT Receptor |
| GR 68755C, GR 68755 Hydrochloride; GR 68755X Hydrochloride | ||
| Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. | ||
| M9014 | RO4987655 | MEK |
| CH4987655 | ||
| RO4987655 is an orally active and highly selective MEK inhibitor with an IC50 of 5.2 nM. | ||
| M10534 | Tucidinostat (Chidamide) HCl | HDAC |
| Chidamide; HBI-8000; CS-055 HCl | ||
| Tucidinostat (HBI-8000; Chidamide; CS-055) HCl is a benzamide type inhibitor of histone deacetylase (HDAC) isoenzymes 1, 2, 3 and 10 with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively. | ||
| M14126 | Avatrombopag hydrochloride | Thrombopoietin/Thrombin |
| AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride | ||
| Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. | ||
| M14526 | Ch55 | RAR/RXR |
| Ch55 is a potent synthetic retinoid. | ||
| M14911 | CH6953755 | Src-bcr-Abl |
| CH6953755 is a potent, orally active and selective YES1 kinase (a member of the SRC family) inhibitor with an IC50 of 1.8 nM. CH6953755 inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo. | ||
| M19867 | Gatifloxacin hydrochloride | Topoisomerase |
| AM-1155 hydrochloride; CG5501 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride | ||
| Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively. | ||
| M28711 | CH1055 | Fluorescent Dye |
| CH1055 is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody. | ||
| M28819 | AG-1478 hydrochloride | EGFR/HER2 |
| Tyrphostin AG-1478 hydrochloride; NSC 693255 hydrochloride | ||
| AG-1478 hydrochloride (Tyrphostin AG-1478 hydrochloride) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 hydrochloride has antiviral effects against HCV and encephalomyocarditis virus (EMCV). | ||
| M29174 | CHMFL-ABL/KIT-155 | Src-bcr-Abl |
| CHMFL-ABL-KIT-155 | ||
| CHMFL-ABL/KIT-155 (CHMFL-ABL-KIT-155; compound 34) is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s of 46 nM and 75 nM, respectively), and it also presents significant inhibitory activities to BLK (IC50=81 nM), CSF1R (IC50=227 nM), DDR1 (IC50=116 nM), DDR2 (IC50=325 nM), LCK (IC50=12 nM) and PDGFRβ (IC50=80 nM) kinases. | ||
| M31067 | CH1055 triethylamine | Fluorescent Dye |
| CH1055 triethylamine is a NIR-II fluorophore based on a synthetic 970-Da organic molecule. CH1055 triethylamine is a rapidly excreted dye (∼90% excreted through the kidneys within 24 h). CH1055 triethylamine also allows targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody. | ||
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