Free shipping on all orders over $ 500

Caspofungin

Cat. No. M3724

All AbMole products are for research use only, cannot be used for human consumption.

Caspofungin Structure
Size Price Availability
5mg USD 60  USD60 Custom Synthesis
10mg USD 100  USD100 Custom Synthesis
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Caspofungin exhibited similar efficacy to TMP-SMZ for enhancing survival and reducing lung edema and cyst load in a rat model of PcP, suggesting potential clinical utility against PcP. It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin is at least as effective as amphotericin B for the treatment of invasive candidiasis and, more specifically, candidemia. Caspofungin may be considered as a component of combination antifungal regimens. Caspofungin represents a significant advance in the care of patients with serious fungal infections.

Chemical Information
Molecular Weight 1093.31
Formula C52H88N10O15
CAS Number 162808-62-0
Solubility (25°C) DMSO ≥ 25 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sun P, et al. Med Mycol. Efficacy of caspofungin, a 1,3-β-D-glucan synthase inhibitor, on Pneumocystis carinii pneumonia in rats.

[2] Morrison VA. Expert Rev Anti Infect Ther. Caspofungin: an overview.

[3] Mora-Duarte J, et al. N Engl J Med. Comparison of caspofungin and amphotericin B for invasive candidiasis.

Related Anti-infection Products
Torcitabine

Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection research. Torcitabine (2'-Deoxy-L-cytidine) shows greater inhibition of first strand than second strand DNA synthesis.

ABMA

ABMA is a broad-spectrum inhibitor of intracellular toxins and pathogens. ABMA efficiently protects cells against various toxins and pathogens including viruses, intracellular bacteria and parasite.

DDX3-IN-1

DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 values of 50 and 36 μM for HIV and HCV, respectively. DDX3-IN-1 has antiviral activity.

WU-04 

WU-04 is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein.

MM3122 

MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Caspofungin supplier, Anti-infection, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.