Cat.No. | Name | Information |
---|---|---|
M49424 | Hirudin | Hirudin is a thrombin inhibitor with anticoagulant properties and strong antifibrotic and antitumor activity. |
M21584 | Protamine sulfate | Protamine sulfate is a positive ionic peptide with anti-heparin activity. Protamine sulfate has strong alkaline groups, which combine with strongly acidic heparin in the body to form a stable compound, making heparin lose its anticoagulant ability. |
M21307 | Romiplostim | Romiplostim binds to and activates the TPO receptor on megakaryocyte precursors, thus promoting cell proliferation and viability, resulting in increased platelet production. |
M21209 | Heparin Lithium salt | Heparin Lithium salt is an anticoagulant that binds reversibly to antithrombin III (ATIII). |
M20996 | Eprotirome (KB2115) | Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR). Eprotirome is investigated for the potential treatment of dyslipidemias and obesity. |
M20971 | Avatrombopag | Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system. |
M14537 | Bivalirudin TFA | Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. |
M14126 | Avatrombopag hydrochloride | Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. |
M9804 | Thrombin | Thrombin is a trypsin-like allosteric serine protease. |
M9458 | Lusutrombopag | Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist. Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels. |
M8658 | Ximelagatran | Ximelagatran is orally active, selective and potent direct thrombin inhibitor. |
M7902 | Metolazone | Inhibitor of thiazide-sensitive Na+-Cl- cotransporter; antihypertensive; moderate "loop" diuretic. |
M6396 | AC 55541 | AC 55541 is a potent and selective PAR2 agonist. |
M4822 | Eltrombopag Olamine | Eltrombopag olamine is a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. |
M3914 | Gallic acid | Gallic acid is an antiinflammatory substance found in plants and has been shown to Induce apoptosis in human lung cancer cells. |
M3759 | Dabigatran etexilate mesylate | Dabigatran etexilate mesylate is a direct thrombin inhibitor. |
M3717 | Argatroban Monohydrate | Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. |
M3574 | Dabigatran Etexilate | Dabigatran Etexilate is the procompound of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. |
M3488 | Eltrombopag | Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). |
M1674 | BIBR 953 | BIBR 953 (Dabigatran, Pradaxa) is an oral anticoagulant from the class of the direct thrombin inhibitors. |
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