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Protamine sulfate is a positive ionic peptide with anti-heparin activity. Protamine sulfate has strong alkaline groups, which combine with strongly acidic heparin in the body to form a stable compound, making heparin lose its anticoagulant ability.
| Formula | H2O4S |
| CAS Number | 9009-65-8 |
| Solubility (25°C) | Water ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Vance G Nielsen, et al. Anesth Analg. Protamine sulfate: crouching clot or hidden hemorrhage?
[4] No authors listed. J Am Med Assoc. PROTAMINE sulfate
[5] R Porsche, et al. Heart Lung. Allergy to protamine sulfate
| Related Thrombopoietin/Thrombin Products |
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Desirudin is a thrombin inhibitor that inhibits thrombosis and venous stasis thrombosis.Desirudin can be used in studies related to thrombocytopenia or platelet dysfunction. |
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TP508 is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. |
| Succinyl-(Pro58, D-Glu65)-Hirudin (56-65) (sulfated)
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. |
| Thrombin receptor peptide ligand
Thrombin receptor peptide ligand is a thrombin receptor antagonist peptide that can be used as an antithrombotic agent. |
| Z-Gly-Pro-Arg-4MβNA
Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). |
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