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Eprotirome (KB2115)

Cat. No. M20996

All AbMole products are for research use only, cannot be used for human consumption.

Eprotirome (KB2115) Structure
Size Price Availability Quantity
5mg USD 58  USD58 In stock
10mg USD 90  USD90 In stock
25mg USD 180  USD180 In stock
50mg USD 280  USD280 In stock
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Quality Control & Documentation
Biological Activity

Eprotirome (KB2115) is a liver-selective agonist of thyroid hormone receptor (TR). Eprotirome is investigated for the potential treatment of dyslipidemias and obesity.

Chemical Information
Molecular Weight 487.14
Formula C18H17Br2NO5
CAS Number 355129-15-6
Solubility (25°C) DMSO 97 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Federica Saponaro, et al. Front Med (Lausanne). Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders

[2] Riccardo Zucchi. Thyroid. Thyroid Hormone Analogues: An Update

[3] Marta Szydlowska, et al. Gene Expr. The Thyromimetic KB2115 (Eprotirome) Induces Rat Hepatocyte Proliferation

[4] Attila Olh, et al. J Invest Dermatol. The Thyroid Hormone Analogue KB2115 (Eprotirome) Prolongs Human Hair Growth (Anagen) Ex Vivo

[5] Paul W Ladenson, et al. N Engl J Med. Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia

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Keywords: Eprotirome (KB2115) supplier, Thrombopoietin/Thrombin, inhibitors, activators

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