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Cimelagatran is an orally active, selective and potent direct thrombin inhibitor. Cimelagatran is a precursor compound of the thrombin inhibitor Melagatran.
| Molecular Weight | 473.57 |
| Formula | C24H35N5O5 |
| CAS Number | 192939-46-1 |
| Form | Solid |
| Solubility (25°C) | DMSO: 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Shir-Jing Ho, et al. Ximelagatran: direct thrombin inhibitor
[2] Anirban Choudhury, et al. Ximelagatran
[3] Lisa Kwok, et al. Ximelagatran: a new type of oral anticoagulant
| Related Thrombopoietin/Thrombin Products |
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| Melagatran
Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. |
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Idraparinux sodium (SANORG 34006) is a long-acting indirect factor Xa inhibitor. |
| Desirudin
Desirudin is a thrombin inhibitor that inhibits thrombosis and venous stasis thrombosis.Desirudin can be used in studies related to thrombocytopenia or platelet dysfunction. |
| TP508
TP508 is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. |
| Succinyl-(Pro58, D-Glu65)-Hirudin (56-65) (sulfated)
Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. |
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