ROCK Rho-associated protein kinase

Cat.No.	Name	Information
M1817	Y-27632 dihydrochloride	Y-27632 is a potent, selective inhibitor of Rho-associated protein kinases (ROCK) with IC50 values of 140-220 nM for ROCK1 and ROCK2. In addition, Y-27632 inhibited LPA-induced entosis.
M5168	GSK269962A	GSK269962A is a potent ROCK inhibitor with IC50 values of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2, respectively.
M7388	TC-S 7001	TC-S 7001 is a potent and highly selective ROCK inhibitor; orally active.
M4938	H-1152	H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
M1856	Thiazovivin	Thiazovivin is a selective small molecule Rho-associated kinase (ROCK) inhibitor which significantly improves (200-fold) the efficiency of iPSC generation from human fibroblasts.
M5123	Y-39983 dihydrochloride	Y-39983 (Y-33075) dihydrochloride is a selective ROCK inhibitor with an IC50 of 3.6 nM, derived from Y-27632, inhibited ROCK more potently than Y-27632.
M49537	Rho-Kinase-IN-2	Rho-Kinase-IN-2 is an orally active, selective, and central nervous system (CNS)-penetrant Rho Kinase (ROCK) inhibitor (ROCK2 IC50=3 nM).
M49536	Rho-Kinase-IN-1	Rho-Kinase-IN-1 is a Rho kinase (ROCK) inhibitor (Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1.008.
M49535	HSD1590	HSD1590 is potent ROCK inhibitor, with IC50s of 1.22 and 0.51 nM for ROCK1 and ROCK2, respectively.
M49534	GSK317354A	GSK317354A is a ROCK and GRK inhibitor.
M49533	GSK269962A hydrochloride	GSK269962A hydrochloride (GSK 269962 hydrochloride) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively.
M49532	GSK-25	GSK-25 is a potent, selective and orally bioavailable ROCK1 inhibitor (IC50=7 nM).
M49531	Glycyl H-1152 hydrochloride	Glycyl H-1152 hydrochloride is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride.
M49530	Chroman 1 dihydrochloride	Chroman 1 dihydrochloride is a highly potent and selective ROCK inhibitor.
M49529	CCG-232964	CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF.
M49527	AR-13324 analog mesylate	AR-13324 analog mesylate is an analog of AR-13324.
M49526	CAY10746	CAY10746 is a selective Rho kinase (ROCK) inhibitor.
M49525	3-(4-Pyridyl)indole	3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM.
M41597	ROCK-IN-9	ROCK-IN-9 is a ROCK inhibitor.
M41596	ROCK-IN-7	ROCK-IN-7 is a ROCK kinase inhibitor.
M41595	ROCK-IN-8	ROCK-IN-8 is a ROCK inhibitor, with an IC50 value less than 100 nM.
M41594	CaMKP inhibitor sodium	CaMKP inhibitor sodium is a selective inhibitor of ROCK1 with an IC50 value of 14 nM.
M41593	Rho-Kinase-IN-3	Rho-Kinase-IN-3 is a potent and selective Rho kinase (ROCK1) inhibitor with an IC50 value of 8 nM.
M41592	THK01	THK01 is a potent ROCK2 inhibitor with IC50 values of 5.7 and 923 nM for ROCK2 and ROCK1, respectively.
M41591	ROCK2-IN-6	ROCK2-IN-6 is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.
M41590	ROCK2-IN-6 hydrochloride	ROCK2-IN-6 hydrochloride is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.

By Signaling Pathways

By Product Type

Signaling Pathways

ROCK Rho-associated protein kinase

Get to Know Us

Customer Support

Resources

Contact Us