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Abmole Inhibitor Catalog 2017

PAR Protease-Activated Receptor


Cat.No.  Name Information
M10143 AZ3451 AZ3451 is a potent PAR2 (protease-activated receptor-2) antagonist with IC50 of 23 nM, which plays a part in inflammation response, apoptosis, autophagy and cellular senescence during Osteoarthritis (OA).
M9814 (Ala1)-PAR-4 (1-6) (mouse) (Ala1)-PAR-4 (1-6) (mouse)
M9813 PAR-4 (1-6) (mouse) PAR-4 (1-6) (mouse)
M9812 PAR-4 (1-6) (human) PAR-4 (1-6) (human) is an N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist.
M6243 Vorapaxar Sulfate Vorapaxar is a first-in-class, potent and orally-active protease-activated receptor 1 (PAR-1) antagonist that blocks thrombin-mediated platelet activation without interfering with thrombin-mediated fibrin deposition.
M3123 Vorapaxar Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM.

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