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Parmodulin 2 (ML161) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.
| Molecular Weight | 361.23 |
| Formula | C17H17BrN2O2 |
| CAS Number | 423735-93-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Robert Flaumenhaft, et al. Targeting PAR1: Now What?
[4] Lynn VerPlank, et al. Chemical Genetic Analysis of Platelet Granule Secretion-Probe 3
| Related PAR Products |
|---|
| ENMD-1068 hydrochloride
ENMD-1068 hydrochloride is a selective protease-activated receptor 2 (PAR2) antagonist. ENMD-1068 hydrochloride reduces hepatic stellate cell activation and collagen expression by inhibiting TGF-β1/Smad signaling. |
| SCH79797 dihydrochloride
SCH79797 dihydrochloride is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist. |
| TRAP-6 amide
TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide. |
| Protease-Activated Receptor-1, PAR-1 Agonist
Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. |
| FSLLRY-NH2
FSLLRY-NH2 is a protease-activated receptor 2 (PAR2) inhibitor. |
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