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ML161

Cat. No. M2574

All AbMole products are for research use only, cannot be used for human consumption.

ML161 Structure

Synonym:

Parmodulin 2

Size	Price	Availability	Quantity
5mg	USD 65 USD65	In stock
10mg	USD 90 USD90	In stock
25mg	USD 180 USD180	In stock

Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation

Purity: 99.77%
COA
MSDS
H-NMR
HPLC

Product Information

Biological Activity

Parmodulin 2 (ML161) is an allosteric inhibitor of PAR1 with IC50 of 0.26 μM.

Chemical Information

Molecular Weight	361.23
Formula	C17H17BrN2O2
CAS Number	423735-93-7
Form	Solid
Solubility (25°C)	DMSO 90 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] Disha M Gandhi, et al. The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability

[2] Hyo-Ju Son, et al. Diagnostic performance of the (1-3)-β-D-glucan assay in patients with Pneumocystis jirovecii compared with those with candidiasis, aspergillosis, mucormycosis, and tuberculosis, and healthy volunteers

[3] Sumra Nazir, et al. Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition

[4] Robert Flaumenhaft, et al. Targeting PAR1: Now What?

[5] Lynn VerPlank, et al. Chemical Genetic Analysis of Platelet Granule Secretion-Probe 3

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Catalog

Abmole Inhibitor Catalog

Keywords: ML161, Parmodulin 2 supplier, PAR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.

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