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p38 MAPK P38 mitogen-activated protein kinases


Cat.No.  Name Information
M1781 Adezmapimod (SB203580) Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM.
M2062 SB 202190 SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase with IC50 values of 50 and 100 nM inhibiting p38α and p38β, respectively.
M20380 WAY-306955 WAY-306955 is a modulator of transcriptional repression.
M20327 GI-505946 GI-505946 is a inhibitor of p38.
M20302 WAY-299819 WAY-299819 altering the lifespan of a eukaryotic organism
M20293 WAY-628644 WAY-628644 is a p38α inhibitor.
M20276 WAY-656283 WAY-656283 is a p38 kinase inhibitor.
M20233 WAY-632613 WAY-632613 is a p38 MAP Kinase inhibitor.
M20228 WAY-630998 WAY-630998 is a inhibitor of p38a kinase.
M20191 WAY-603359 WAY-603359 altering the lifespan of a eukaryotic organism
M20082 WAY-313013 WAY-313013 is a p38a Mitogen-Activated Protein Kinase inhibitor
M20042 WAY-270968 WAY-270968 is a p38 MAP Kinase inhibitor.
M20041 WAY-270966 WAY-270966 is a p38 MAP Kinase inhibitor.
M14180 Talmapimod Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM.
M14179 SB 242235 SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC50 of 1.0 μM in primary human chondrocytes.
M14178 p38 MAPK-IN-1 p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability.
M14177 p38-α MAPK-IN-1 p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay.
M14176 MAPK13-IN-1 MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.
M14175 Esculin Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark.
M14174 BMS-582949 hydrochloride BMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM. BMS-582949 hydrochloride displays a significantly improved pharmacokinetic profile and is effective in inflammatory disease.
M14165 MK2-IN-1 hydrochloride MK2-IN-1 hydrochloride is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.
M14164 GNE-3511 GNE-3511 is a dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM.

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