| Cat.No. | Name | Information |
|---|---|---|
| M2062 | SB 202190 | SB 202190 is a highly selective, potent and cell permeable inhibitor of p38 MAP kinase with IC50 values of 50 and 100 nM inhibiting p38α and p38β, respectively. |
| M1781 | Adezmapimod (SB203580) | Adezmapimod (SB203580) is a P38 MAPK inhibitor with an IC50 of 0.3-0.5 μM, which is 10 times less selective than SAPK3(106T) and SAPK4(106T), and inhibits PKB phosphorylation with an IC50 of 3-5 μM. |
| M54759 | HWY336 | HWY336 is a selective, non-ATP competitive dual MKK4 and MKK7 inhibitor with IC50 values of 6 µM on MKK4 and 10 µM on MKK7 in vitro. HWY336 inhibits the phosphorylation of MKK4/MKK7 inside the activation loop or hinders the substrate to access the kinase. |
| M28610 | TAK1-IN-4 | TAK1-IN-4 (Compound 14) is a TAK1 inhibitor. |
| M21038 | MK2 Inhibitor III | MK2 Inhibitor III (MK2-IN-3) is an ATP-competitive MK2 (MAPKAP-K2) inhibitor with an IC50 value of 8.5 nM. |
| M19388 | Chicanin | Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity. |
| M18061 | 3,4-Dihydroxybenzenepropanoic acid | 3,4-Dihydroxybenzenepropanoic acid is a microbial metabolite of flavonoids, reduces phosphorylation of MAPK p38, with antioxidant potential and anti-inflammatory activity. |
| M14180 | Talmapimod | Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. |
| M14179 | SB 242235 | SB-242235 is a potent and selective p38 MAP kinase inhibitor, with an IC50 of 1.0 μM in primary human chondrocytes. |
| M14178 | p38 MAPK-IN-1 | p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability. |
| M14177 | p38-α MAPK-IN-1 | p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay. |
| M14176 | MAPK13-IN-1 | MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM. |
| M14175 | Esculin | Esculin, a fluorescent coumarin glucoside, is an active ingredient of ash bark. |
| M14164 | GNE-3511 | GNE-3511 is an orally active, bioavailable and brain-permeable dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM.GNE-3511 can be used in studies related to neurodegenerative diseases. |
| M11380 | Gossypetin | Gossypetin, a hexahydroxylated flavonoid, is an effective inhibitor of MKK3 and MKK6, which can strongly weaken the mKK3/6-P38 signal transduction pathway and has a variety of pharmacological activities, including antioxidant, antibacterial and anticancer activities. |
| M10551 | Gypenoside L | Gypenoside L activates p38 and ERK MAPK pathways and NF-κB pathway to induce senescence, it is a saponin that can be found in Gynostemma pentaphyllum. |
| M9229 | GS-444217 | GS-444217 is a potent and selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87±0.85 nM. |
| M9160 | BMS-582949 | BMS-582949 is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibitor with IC50 of 13nM. |
| M9013 | R1487 Hydrochloride | R1487 Hydrochloride is an orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase. |
| M8991 | Dilmapimod | Dilmapimod (also known as SB-681323 and GW-681323) is a p38 MAPK inhibitor that potentially suppresses inflammation in COPD. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
