Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M5363 | 3-Pyridinemethanol | 3-Pyridinemethanol is a useful synthetic intermediate. |
M5360 | 2-Aminoheptane | 2-Aminoheptane is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor. |
M5359 | 2,2′-Dihydroxy-4-methoxybenzophenone | Dioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays. |
M5354 | (R)-Oxiracetam | (R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant. |
M5353 | (R)-(-)-Modafinic acid | (R)-(-)-Modafinic acid(Armodafinic acid) is the major metabolite of Modafinil, which is a central nervous system vigilance promoting agent, which posseses neuroprotective properties. |
M5220 | Piperlongumine | Piperlongumine, a natural alkaloid from Piper longum L., is also a direct TrxR1 inhibitor with suppressive activity against gastric cancer and a novel inhibitor of CRM1. |
M5218 | AZ191 | AZ191 is a potent small molecule inhibitor that selectively inhibits DYRK1B in vitro and in cells. |
M5217 | AI-10-49 | AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM. |
M5180 | Quercetin hydrate | Quercetin hydrate |
M5178 | 8-Prenylchrysin | 8-Prenylchrysin |
M5176 | Isowighteone | isowighteone |
M5082 | α-Cyclodextrin | α-CD has a smaller cavity size than β-CD, so it is more suitable for inclusion of small molecules in inclusions, and applications that require high CD solubility. |
M5067 | Eluxadoline | Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist. |
M5063 | DDR1-IN-1 | DDR1-IN-1 is a potent and selective discoidin domain receptor 1 (DDR1) receptor tyrosine kinase inhibitor with IC50 of 105 nM, about 3-fold selectivity over DDR2. |
M5056 | Etofylline | Etofylline is a vasodilator. Etofylline is also an anticholesteremic and reduces total cholesterol level in the blood. |
M5047 | ML216 | ML216 is a potent inhibitor of the DNA unwinding activity of BLM helicase; showing similar IC50s of 3.0 and 0.97 μM for full length BLM and BLM636–1298 respectively. |
M5043 | 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine | 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is an important pharmaceutical intermediate, which is widely used in the synthesis of many pharmaceutical intermediates at home and abroad. Including CP690550, CGP76030 and so on, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the scaffold for many commercially available drugs. Also, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine was the intermediate of the bulk drug, Tofatinib, which was widely used in treatment of adult patients with moderate to severe rheumatoid arthritis with inadequate or intolerant methotrexate response. |
M5011 | Propargyl Methacrylate | |
M5007 | Hexyl Chloroformate | The Carbonochloridic acid,hexyl ester, belongs to the following product categories: (1)Acid Halides; (2)Carbonyl Compounds; (3)Organic Building Blocks. It has the systematic name of hexyl carbonochloridate. |
M5006 | 2,3'-Dichloroacetophenone | Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders. |
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