| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7967 | NN-DNJ | Nn-dnj is a glucosidase inhibitor that acts as a compound chaperone. |
| M7965 | Neridronate | Neridronate is a bone resorption inhibitor. |
| M7962 | NBI 27914 | NBI 27914 is a CRF1 corticotropin-releasing factor receptor antagonist. |
| M7957 | (+)-Norfenfluramine hydrochloride | (+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release. |
| M7956 | Necrostatin-7 | Necrostatin-7 (Nec-7) is a potent inhibitor of necroptosis, a regulated caspase-independent necrotic cell death pathway, distinct from apoptosis. |
| M7955 | Nucleozin | Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. |
| M7954 | NP603 | NP603 is a cell-permeable inhibitor of PDGFRβ, FGFR1 and VEGFR2 that binds to ATP pocket. |
| M7953 | NKY80 | NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform. |
| M7951 | Naltrindole isothiocyanate hydrochloride | Naltrindole isothiocyanate hydrochloride is a selective irreversible δ2 opioid receptor antagonist. |
| M7948 | NO-711 hydrochloride | NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier. |
| M7947 | NSCI | NSCI is a nonpeptide caspase 3 selective inhibitor. |
| M7946 | Naloxone methiodide | Quaternary salt of naloxone that, like the parent compound, is a nonselective antagonist at opioid receptors. |
| M7944 | NSC43067 | NSC43067 is a Cyclin-dependent kinase (Cdk) inhibitor which binds to a novel conserved site on Cdk, presumably the p27 binding pocket. |
| M7943 | NAEPA | Selective lysophosphatidic acid-1 (LPA1) receptor agonist; LPA mimetic. |
| M7941 | H-8 dihydrochloride | cAMP and cGMP-dependent protein kinase inhibitor. |
| M7937 | MADAM dihydrochloride | High affinity ligand for the serotonin transporter SERT. |
| M7935 | ML 10302 | Potent, selective 5-HT4 serotonin receptor agonist. |
| M7933 | (+)-Muscarine chloride | Prototype muscarinic acetylcholine receptor agonist; active enantiomer. |
| M7932 | MRS 2395 | Antagonist for P2Y12 purinoceptor; inhibits ADP-induced aggregation in rat platelets and antagonizes ADP-induced inhibition of cAMP in rat and human platelets in the presence of PGE1 without affecting P2Y1 receptor-induced PLC activity in transfected astrocytoma cells. |
| M7931 | MBX-102 acid | MBX-102 is a selective PPAR modulator (SPPARM) and has been shown to inhibit phosphorylation of PPARγ. |
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