| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9331 | 10-Hydroxy-trans-2-decenoic acid | 10-hydroxy-2-decenoic acid (10-H2DA) is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. |
| M13422 | Beloranib | Beloranib is a methionine aminopeptidase 2 (METAP2) inhibitor. It's an experimental compound candidate for obesity research. |
| M13420 | BAY-784 | BAY-784 is a gonadotropin-releasing hormone receptor (GnRH-R) antagonist (IC50s: 21 and 24 nM for human and rat GnRH-R). |
| M13419 | NBI 42902 | NBI-42902 is an effective inhibitor of peptide radioligand binding to human GnRH receptor (K(I)=0.56 nm). Tritiated NBI-42902 binds to a single class of binding sites with high affinity (K(d)=0.19 nm) and can be replaced by a range of peptide and non-peptide GnRH receptor ligands. |
| M13418 | acyline | It is a GnRH (LHRH) antagonist. |
| M13417 | Ozarelix | Ozarelix is a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors. Sequence: Ac - D - 2-4 - Cpa - D - Nal - D - 3 - Pal - Ser - N - Me - Tyr - D - Hci - Nle - Arg - Pro - D - Ala - NH2 |
| M13416 | SPR206 acetate | SPR206 acetate is a polymycolistin analogue. The MIC value of SPR206 acetate against Pa14 and ACinetobacter baumannii NCTC13301 is 0.125 mg/L. |
| M13415 | Avarofloxacin | Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial compound used in the study of acute bacterial skin infections and acquired pneumonia. Avarofloxacin (JNJ-Q2) is an aminoethyl piperidine fluoroquinolone with an average MIC90 value of 0.12 mg/L. |
| M13410 | R-1479 | R-1479, a nucleoside analogue, is a HCV replication inhibitor (IC50: 1.28 μM) in the HCV subgenomic replication subsystem. |
| M13408 | SNAP 94847 hydrochloride | SNAP 94847 Hydrochloride is a novel high affinity selective melanin concentration hormone receptor 1 (MCHR1) antagonist with antidepressant like activity. SNAP 94847 Hydrochloride is a high-affinity antagonist (pA2=7.81) of MYo-inositol phosphate formation induced by MCH. |
| M13399 | CE-245677 | CE-245677 is a potent and reversible inhibitor of Tie2 and TrkA/B, with IC50 values of 4.7 and 1 nM, respectively, in the cellular system. |
| M13364 | Tricyclazole | Tricyclazole is a biosynthetic inhibitor of pentaketone melanin and a unique fungicide for rice blast control. |
| M11536 | Coumarin 2 | 7-(ethylamino)-4,6-dimethylchromen-2-one |
| M11458 | Framycetin | Framycetin (Neomycin B) is an aminoglycoside antibiotic, which is an effective inhibitor of RNase P cleavage activity with Ki of 35 μM. |
| M11445 | CHF-6366 | CHF-6366 is a muscarinic antagonist and β2 agonist (MABA) being developed as an inhaled treatment for respiratory diseases. |
| M11439 | NCGC00138783 | NCGC00138783 selectively blocked the interaction of CD47/SIRPα with IC50 of 40 μM. NCGC00138783 does not disrupt the binding of CD47/SIRPα to other receptors. |
| M11437 | SEN177 | |
| M11435 | ABR-238901 | Abr-238901 is an orally effective S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE (receptor for advanced glycation end products) and TLR4(Toll-like receptor 4). Abr-238901 has the potential to be used in myocardial infarction (MI) research. |
| M11430 | Desethyl chloroquine diphosphate | Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine is an inhibitor of autophagy and Toll-like receptors (TLRs). Desethyl Chloroquine diphosphate has anti-plasmodium activity. |
| M11293 | Pentetreotide | Pentetreotide is a polypeptide. |
| M11291 | FAPI-46 | Fei-46 is a quinoline-based radiotracer targeting fibroblast activating protein (FAP). Fei-46 has a higher tumor absorption rate and increased tumor accumulation time. Fei-46 can be used for tumor imaging in a variety of different cancers. |
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