Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M40862 | Plaunotol | Plaunotol is an acyclic diterpenoid extracted from the stems and leaves of the Croton plant and can be used in studies related to gastric ulcers. |
M40813 | JNT-517 | JNT-517 is a potentially first-in-class, orally active, variant SLCA6A19 inhibitor for phenylketonuria-related studies. |
M40763 | 4A7C-301 | 4A7C-301 is a compound that activates the Nurr1 protein, binds to Nurr1, and increases its ability to increase its levels in cells exposed to MPP +. In addition, 4A7C-301 ameliorated motor and olfactory deficits in mice modeled with Parkinson's disease and possessed neuroprotective as well as brain permeability activities. |
M40762 | BIA 28-6156 | BIA 28-6156 is an orally active beta-glucocerebrosidase (GCase) variant activator that improves lysosomal function through activation of GCase and can be used in studies related to Parkinson's disease (PD) with GBA gene mutations. |
M40694 | RIG012 | RIG012 is a potent RIG-I antagonist that blocks RIG-I-initiated signaling, inhibits transcriptional induction of CXCL10, IFN-β 1, and IRF9, and reduces IL6 mRNA levels. The IC50 was 0.71 μM when assayed with NADH-coupled ATPase. |
M40681 | KM04416 | KM04416 is an isothiazolone derivative and a potent 3-phosphoglycerol dehydrogenase (GPD2) inhibitor that significantly inhibits PNT1A cell proliferation. |
M40677 | Seongsanamide D | Seongsanamide D is a bicyclic peptide isolated from Bacillus maritimus, a member of the phylum Porifera, containing isodityrosine-bonded residues with antiallergic activity. |
M40676 | Seongsanamide C | Seongsanamide C is a bicyclic peptide isolated from Bacillus maritimus, a member of the phylum Porifera, containing isodityrosine-bonded residues with antiallergic activity. |
M40675 | Seongsanamide B | Seongsanamide B is a bicyclic peptide isolated from Bacillus maritimus, a member of the phylum Porifera, containing isodityrosine-bonded residues with antiallergic activity. |
M40674 | Seongsanamide A | Seongsanamide A is a bicyclic peptide isolated from Bacillus maritimus, a member of the phylum Porifera, containing isodityrosine-bonded residues with antiallergic activity. |
M40673 | Nyuzenamide C | Nyuzenamide C, a cyclic peptide with a heterodityrosine bond found in aquatic bacteria of the genus Streptomyces, bearing a cinnamic acid structural unit, showed anti-angiogenic activity in cell culture assays. |
M40670 | Theopalauamide | Theopalauamide is a bicyclic peptide from the genus Theonella of sponges, constructed via a histidine alanine bridge. |
M40662 | A2A/A3 AR antagonist-1 | A2A/A3 AR antagonist-1 is an adenosine receptor A2A/A3 fluorescent ligand with Ki values of 90 nM and 31.8 nM for hA2A AR and hA3 AR, respectively. |
M40656 | Thyrotropin | Thyrotropin is a thyroid-stimulating hormone produced by thyroid-stimulating cells in the anterior pituitary gland that regulates the endocrine function of the thyroid gland. |
M40646 | CDX-1140 | CDX-1140 is an anti-CD40 human IgG2 monoclonal antibody that activates dendritic cells and B cells and drives NF-kB stimulation in CD40-expressing reporter cell lines. |
M40645 | SL-172154 | SL-172154 is a novel fusion protein consisting of human SIRPα and CD40L (SIRPα-Fc-CD40L) linked by human Fc, which can block the CD47 immune checkpoint and activate the CD40 pathway through the dual mechanism of checkpoint blockade and TNF activation. |
M40636 | NJH-04-087 | NJH-04-087 is a CRBN-KEAP1 ligand degrader. |
M40616 | ALTO-100 | ALTO-100 is an orally active compound that targets brain-derived neurotrophic factor (BDNF) for studies related to depressive disorders. |
M40586 | YH14617 | YH14617 is a synthetic peptide that is also an inhibitor of LAG3 and TIM3 and can be used in studies related to Parkinson's (PD) and diabetes. |
M40552 | Osemitamab | Osemitamab (TST001) is a recombinant humanized, IgG1 antibody targeting CLDN18.2, consisting of the human mouse monoclonal TST001 γ-1 chain polymerized via disulfide bonding with the human mouse monoclonal TST001 κ-chain dimer (ACI). It can be used in studies related to bile duct tumors. |
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