| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M41392 | Velaglucerase alfa | Velaglucerase alfa is produced through gene activation technology and is identical to wild-type enzyme. |
| M41391 | 4-Fluorohippuric acid | 4-Fluorohippuric acid is a major metabolite of flupirtine with research potential against pain and epilepsy. |
| M41390 | Octyl β-D-thioglucopyranoside | Octyl β-D-thioglucopyranoside is a non-ionic detergent that can be used in the field of membrane biochemistry. |
| M41389 | Chymase | Chymase is a protein-digester enzyme found primarily in mast cells (MC), fibroblasts, and vascular endothelial cells. |
| M41388 | Peptone from casein | Peptone from casein is derived from casein hydrolysis, casein is hydrolyzed by pancreatic enzymes and refined into peptone. |
| M41372 | TS-IN-2 | TS-IN-2 is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. |
| M41371 | DG1 | DG1 is a Thymidylate Synthase (TS) inhibitor that affects cancer angiogenesis and metabolic reprogramming in NSCLC cells. |
| M40991 | Icosabutate | Icosabutate is an orally active omega-3 polyunsaturated fatty acid and an eicosapentaenoic acid derivative (EPA derivative) that has been used in studies related to non-alcoholic steatohepatitis (NASH). |
| M40983 | AZD-2693 | AZD-2693 is an antisense oligonucleotide and also a PNPLA3 inhibitor that can be used in studies related to non-alcoholic steatohepatitis (NASH). |
| M40956 | Olezarsen | Olezarsen, an N-acetylgalactosamine (GalNAc)-suffixed antisense oligonucleotide (ASO) targeting hepatic APOC3 mRNA, inhibits the production of apolipoprotein C-III (apoC-III) and can be used in studies related to familial celiac sprue syndrome (FCS). |
| M40954 | Lumasiran | Lumasiran is a siRNA compound that reduces hepatic oxalate production by targeting ethanoic acid oxidase. It can be used in studies related to primary hyperoxaluria type 1 (PH1). |
| M40953 | Givosiran | Givosiran is a small interfering RNA that targets hepatic aminofibrillar synthase 1 (ALAS1) messenger RNA, down-regulates ALAS1 mRNA, and prevents the accumulation of neurotoxic α-aminofibrillar acids and porphyrins, which can be used in porphyria-related studies. |
| M40951 | Viltolarsen | Viltolarsen is a phosphorodiamidomorpholine antisense oligonucleotide that targets splicing of exon 53 of the myotonic dystrophy protein gene and can be used in the study of Duchenne muscular dystrophy (DMD). |
| M40950 | Golodirsen | Golodirsen is a phosphodiesteric morpholino oligomer (PMO) that specifically targets exon 53 of the pre-protein mRNA of myotonic dystrophy protein culture proteins, and can be used in studies related to Duchenne muscular dystrophy (DMD). |
| M40949 | Eteplirsen | Eteplirsen is a synthetic antisense oligonucleotide that can be used in studies related to Duchenne muscular dystrophy (DMD). |
| M40948 | Volanesorsen | Volanesorsen is an antisense oligonucleotide that targets apolipoprotein C-III (APOC3) mRNA and can be used in studies related to familial celiac disease syndrome. |
| M40937 | Suciraslimab | Suciraslimab is a potentially first-in-class monoclonal antibody against the B-cell target CD22, which can help change CD22 from cis-binding to trans-binding and form a stable CD22 trans-binding structure, thereby restoring B-cell tolerance to its own antigens and inhibiting B-cells from undergoing a series of related immune responses to attack its own organism. |
| M40933 | BGB-30813 | BGB-30813 is a DGKζ inhibitor that can be used in studies related to solid tumors.DGKζ is a member of the diacylglycerol kinase (DGK) family of phosphatidylglycerol kinases, which plays an important role in the regulation of a variety of cell signaling pathways. |
| M40910 | Triolex | Triolex is an ERK as well as nuclear factor κB inhibitor inhibitor that selectively inhibits the inflammatory ERK signaling pathway and may reduce neuroinflammation by inhibiting inflammation-driven insulin resistance and major pathological inflammatory cascades. It can be used in studies related to Alzheimer's disease (AD). |
| M40897 | HBTU | HBTU is a coupling agent for peptide synthesis with low racemization, simple reaction conditions and short reaction times. |
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