Cat.No. | Name | Information |
---|---|---|
M54086 | Senktide | Senktide is a tachykinin NK3 receptor agonist. |
M53955 | Neurokinin A TFA | Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. |
M53898 | Neurokinin A | Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. |
M53056 | [Lys5, MeLeu9, Nle10]Neurokinin A(4-10) | [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), an analogue of Neurokinin A, is a selective and potent NK2R agonist. |
M40803 | Pavinetant | Pavinetant is a neurokinin-3 receptor (NK3R) antagonist that may be used in studies related to hot flashes and polycystic ovary syndrome. |
M31366 | Elinzanetant | Elinzanetant (NT-814) is a first-in-class, orally active dual neurokinin receptor NK1/NK3 antagonist for studies related to hot flushes (HFs). |
M30886 | Rolapitant hydrochloride hydrate | Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model. |
M30382 | Tradipitant | Tradipitant (VLY-686) is a neurokinin-1 (NK-1) antagonist. |
M27671 | Vapreotide | Vapreotide is a neurokinin-1 (NK1) receptor antagonist, with an IC50 of 330 nM. |
M25564 | Substance P (6-11) | Substance P (6-11) is the C-terminal hexapeptideamide of Substance P. Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect. |
M14024 | Substance P TFA | Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). |
M14021 | Fezolinetant | Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R), used for the treatment of menopausal hot flushes. |
M10332 | Vapreotide acetate | Vapreotide acetate (BMY-41606 acetate; RC160 acetate) is a neurokinin-1 (NK1) receptor antagonist with IC50 value of 330 nM. |
M9080 | Substance P | Substance P is a neuropeptide, acting as a neurotransmitter and as a neuromodulator.The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R). |
M9019 | Rolapitant | Rolapitant (SCH619734) is an orally bioavailable, centrally-acting, selective neurokinin 1 receptor (NK1-receptor) antagonist with a Ki of 0.66 nM. |
M7735 | CP-96345 | CP-96345 is a highly potent and selective, orally active tachykinin and substance P receptor non-peptide inhibitor. |
M7258 | SB 223412 | SB 223412 is a potent, selective non-peptide NK3 antagonist. Brain penetrant. |
M3882 | Netupitant | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM. |
M2712 | Fosaprepitant dimeglumine salt | Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended |
M2673 | Eprazinone dihydrochloride | Eprazinone is a mucolytic. |
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