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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M14568 | Rasagiline | Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively. |
| M14567 | Pargyline | Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively. Pargyline has antihypertensive and anticancer activities. |
| M14566 | (2-Chloropyridin-4-yl)methanamine hydrochloride | (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM. |
| M14565 | Isocarboxazid | Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. |
| M14564 | Iproniazid | Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity. |
| M14563 | 4-Hydroxyderricin | 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. |
| M14235 | Reserpine hydrochloride | Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2). |
| M14234 | NBI-98782 | NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97 nM. |
| M10956 | PAT-1251 | PAT-1251 is a potent, selective, orally lysanyl oxidase-like protein 2 (LOXL2) inhibitor of hLOXL2 and hLOXL3 IC50 The values were 0.71 and 1.17 μM, respectively, and the inhibition of LOXL2 in mice, rats, and dogs was strong.IC50 Values are 0.10, 0.12, and 0.16 μM, respectively; PAT-1251 can be used for studies of a variety of fibrous diseases. |
| M10572 | Paeonol | Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. |
| M9663 | PXS-4728A | PXS-4728A is a selective and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor. |
| M9485 | Eprobemide | Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. |
| M9090 | Tranylcypromine hemisulfate | Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). |
| M8804 | Toloxatone | Toloxadone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant compound. |
| M8020 | Phenelzine sulfate salt | Phenelzine sulfate is a non-selective MAO-A/B inhibitor. |
| M5915 | Radafaxine HCl | Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. |
| M5860 | Pargyline HCl | Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. |
| M5710 | Iproniazid phosphate | Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. |
| M4531 | Rosiridin | Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38). |
| M2006 | Safinamide Mesylate | Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor. |
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