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Monoamine Oxidase Monoamine Oxidase

Inhibitors

Cat.No.  Name Information
M14568 Rasagiline Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively.
M14567 Pargyline Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with Kis of 13 μM and 0.5 μM for MAO-A and MAO-B, respectively. Pargyline has antihypertensive and anticancer activities.
M14566 (2-Chloropyridin-4-yl)methanamine hydrochloride (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.
M14565 Isocarboxazid Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro.
M14564 Iproniazid Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity.
M14563 4-Hydroxyderricin 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM.
M14235 Reserpine hydrochloride Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 (VMAT2).
M14234 NBI-98782 NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97 nM.
M10956 PAT-1251 PAT-1251 is a potent, selective, orally lysanyl oxidase-like protein 2 (LOXL2) inhibitor of hLOXL2 and hLOXL3 IC50 The values were 0.71 and 1.17 μM, respectively, and the inhibition of LOXL2 in mice, rats, and dogs was strong.IC50 Values are 0.10, 0.12, and 0.16 μM, respectively; PAT-1251 can be used for studies of a variety of fibrous diseases.
M10572 Paeonol Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
M9663 PXS-4728A PXS-4728A is a selective and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor.
M9485 Eprobemide Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination.
M9090 Tranylcypromine hemisulfate Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO).
M8804 Toloxatone Toloxadone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant compound.
M8020 Phenelzine sulfate salt Phenelzine sulfate is a non-selective MAO-A/B inhibitor.
M5915 Radafaxine HCl Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.
M5860 Pargyline HCl Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.
M5710 Iproniazid phosphate Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.
M4531 Rosiridin Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38).
M2006 Safinamide Mesylate Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor.



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