Cat.No. | Name | Information |
---|---|---|
M29602 | LOX-IN-3 dihydrochloride | LOX-IN-3 dihydrochloride is an orally active lysyl oxidase (LOX) inhibitor. LOX-IN-3 dihydrochloride can be used for fibrosis, cancer and angiogenesis research. |
M29601 | LOX-IN-3 | LOX-IN-3 is an orally active lysyl oxidase (LOX) inhibitor. LOX-IN-3 can be used for fibrosis, cancer and angiogenesis research. |
M29270 | PXS-5153A | PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis. |
M29269 | PXS-5120A | PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8). |
M21727 | Azure B | Azure B |
M19368 | Osthenol | Osthenol (Ostenol) is a selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B. |
M17950 | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;Obtusin | 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;Obtusin |
M14566 | (2-Chloropyridin-4-yl)methanamine hydrochloride | (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM. |
M10572 | Paeonol | Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. |
M9663 | PXS-4728A | PXS-4728A is a selective and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor. |
M9485 | Eprobemide | Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination. |
M9090 | Tranylcypromine hemisulfate | Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO). |
M8804 | Toloxatone | Toloxadone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant compound. |
M8020 | Phenelzine sulfate salt | Phenelzine sulfate is a non-selective MAO-A/B inhibitor. |
M6026 | Tranylcypromine (2-PCPA) HCl | Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively. |
M5915 | Radafaxine HCl | Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. |
M5860 | Pargyline HCl | Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. |
M5783 | Methylene Blue | Methylene Blue is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase. |
M5710 | Iproniazid phosphate | Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class. |
M4531 | Rosiridin | Rosiridin inhibits MAO A and MAO B and has A potential role in depression and alzheimer's disease. The inhibition rate of Rosiridin against MAO B at 10 μM was 83.8% (pIC50=5.38). |
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