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Monoamine Oxidase Monoamine Oxidase

Cat.No.  Name Information
M49484 PF9601N PF9601N is a monoamine oxidase B (MAO-B) inhibitor with neuroprotective properties in various ex vivo and in vivo models of Parkinson's disease (PD) for the study of excitotoxicity-mediated neurodegenerative diseases. In addition, PF9601N is a click chemistry reagent containing an Alkyne moiety that undergoes a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide moiety.
M30162 Harmol  Harmol is an orally active monoamine oxidase (MAO) inhibitor that has anti-tumor, anti-depressant, and anti-aging effects. Harmol is a TFEB activator. Harmol can induce cell mitosis, autophagy and apoptosis. Harmol promotes the degradation of α-synuclein through the regulation of the autophagy-lysosomal pathway, improving motor deficits in mouse models of Parkinson's disease.
M29602 LOX-IN-3 dihydrochloride  LOX-IN-3 dihydrochloride is an orally active lysyl oxidase (LOX) inhibitor. LOX-IN-3 dihydrochloride can be used for fibrosis, cancer and angiogenesis research.
M29601 LOX-IN-3  LOX-IN-3 is an orally active lysyl oxidase (LOX) inhibitor. LOX-IN-3 can be used for fibrosis, cancer and angiogenesis research.
M29270 PXS-5153A  PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.
M29269 PXS-5120A  PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8).
M24611 Simtuzumab Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC).
M19368 Osthenol Osthenol (Ostenol) is a selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B.
M17950 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;Obtusin 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione;Obtusin
M14566 (2-Chloropyridin-4-yl)methanamine hydrochloride (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM.
M14563 4-Hydroxyderricin 4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM.
M10572 Paeonol Paeonol is an active extraction from the root of Paeonia suffruticosa, Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
M9663 PXS-4728A PXS-4728A is a selective and orally active semicarbazide-sensitive amine oxidase (SSAO) inhibitor.
M9485 Eprobemide Eprobemide is a non-competitive reversible inhibitor of monoamine oxidase A that exhibits selective action on serotonin deamination.
M9090 Tranylcypromine hemisulfate Tranylcypromine hemisulfate is a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO).
M8804 Toloxatone Toloxadone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant compound.
M6026 Tranylcypromine (2-PCPA) HCl Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively. Tranylcypromine hydrochloride inhibits LSD1, MAO A and MAO B with IC50s of 20.7, 2.3 and 0.95 μM, respectively.
M5860 Pargyline HCl Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension.
M5783 Methylene Blue Methylene Blue is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase.
M5710 Iproniazid phosphate Iproniazid is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class.




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