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PXS-5120A is a potent, irreversible fluoroallylamine inhibitor of Lysyl Oxidase-like 2/3 (LOXL2/3) with anti-fibrotic activity. PXS-5120A is >300-fold selective for LOXL2 (Ki of 83 nM; pIC50 of 8.4) over LOXL (pIC50 of 5.8).
| Molecular Weight | 481.97 |
| Formula | C22H25ClFN3O4S |
| CAS Number | 2125955-70-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 125 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related Monoamine Oxidase Products |
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| Moclobemide N-Oxide
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