Free shipping on all orders over $ 500

Osthenol

Cat. No. M19368

All AbMole products are for research use only, cannot be used for human consumption.

Osthenol Structure
Size Price Availability Quantity
1mg USD 110  USD110 In stock
5mg USD 220  USD220 In stock
10mg USD 330  USD330 In stock
20mg USD 440  USD440 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Osthenol (Ostenol) is a selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B.

Chemical Information
Molecular Weight 230.26
Formula C14H14O3
CAS Number 484-14-0
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jia-Ming Guo, et al. Zhongguo Zhong Yao Za Zhi. [Chemical constituents from Clausena excavata and their inhibitory activities against proliferation of synoviocytes]

[2] Piljoung Cho, et al. Xenobiotica. Characterization of osthenol metabolism in vivo and its pharmacokinetics

[3] Seung Cheol Baek, et al. Bioorg Med Chem Lett. Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity

[4] Pil Joung Cho, et al. Pharmaceutics. Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol

[5] X Lv, et al. Xenobiotica. Isolation and identification of metabolites of osthole in rats

Related Monoamine Oxidase Products
Clorgyline

Clorgyline (M&B 9302) is an orally active, blood-brain barrier permeable and selective monoamine oxidase A (MAO-A) inhibitor.

MAO-B-IN-2 

MAO-B-IN-2 is a selective and competitive inhibitor of MAO-B and BChE with IC50 values of 0.51 and 7.00 μM, respectively.

Befloxatone

Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM).

Moclobemide N-Oxide

Moclobemide N-Oxide (Ro 12-5637) is N-oxide metabolite of Moclobemide.

Indazole

Indazole, also called isoindazole, a heterocyclic aromatic organic compound.

  Catalog
Abmole Inhibitor Catalog




Keywords: Osthenol supplier, Monoamine Oxidase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.