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PXS-5153A 

Cat. No. M29270

All AbMole products are for research use only, cannot be used for human consumption.

PXS-5153A  Structure
Size Price Availability Quantity
5mg USD 330  USD330 In stock
10mg USD 500  USD500 In stock
25mg USD 850  USD850 In stock
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Quality Control & Documentation
Biological Activity

PXS-5153A is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A could reduce crosslinks and ameliorates fibrosis.

Chemical Information
Molecular Weight 475.41
Formula C20H25Cl2FN4O2S
CAS Number 2125956-82-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yordanos F I Setargew, et al. Cancers (Basel). Targeting Lysyl Oxidase Family Meditated Matrix Cross-Linking as an Anti-Stromal Therapy in Solid Tumours

[2] Heidi Schilter, et al. J Cell Mol Med. The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis

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  Catalog
Abmole Inhibitor Catalog




Keywords: PXS-5153A  supplier, Monoamine Oxidase, inhibitors, activators

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