| Cat.No. | Name | Information |
|---|---|---|
| M5783 | Methylene Blue | Methylene Blue is used as a dye in chromoendoscopy. It Inhibits tau filament formation with IC50 of 1.9μM. Also it inhibits soluble guanylyl cyclase. |
| M14566 | (2-Chloropyridin-4-yl)methanamine hydrochloride | (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor with an IC50 of 126 nM. |
| M42685 | MAO-B-IN-3 | MAO-B-IN-3 is a reversible and selective MAO-B inhibitor (IC50=96 nM). |
| M42684 | Pheniprazine hydrochloride | Pheniprazine hydrochloride is a potent and long acting inhibitor of monoamine oxidase. |
| M42683 | Tisolagiline | Tisolagiline (KDS2010) is a reversible MAO-B inhibitor used in Parkinson's disease research. |
| M42682 | Pimprinine | Pimprinine is a potent monoamine oxidase inhibitor, could be isolated from fermented broths. |
| M42681 | MAOA-IN-1 | MAOA-IN-1 is an orally active MAOA inhibitor with cytotoxicity against prostate cancer cells. |
| M42680 | Methyl piperate | Methylpiperic acid is a piperine alkaloid with significant MAO inhibitory activity (IC503.6 μM). |
| M42679 | MAO-B-IN-21 | MAO-B-IN-21 is an excellent MAO-B inhibitor with antioxidant activity and anti-Aβ aggregation activity. |
| M42678 | MAO A/HSP90-IN-2 | MAO A/HSP90-IN-2 is a dual inhibitor of HSP90and MAO A with the IC50 values of 0.016 and 4.58 μM, respectively. |
| M42677 | MAO-B-IN-18 | MAO-B-IN-18 is a potent and selective MAO B inhibitor with IC50s of 52 nM and 14 μM for hMAO B and hMAO A, respectively. |
| M42676 | MAO A/HSP90-IN-1 | MAO A/HSP90-IN-1 is a MAO A/HSP90 dual inhibitor with IC50 value of 1.77 μM and 0.019 μM in Glioblastoma (GBM) GL26 cells and HSP90α, respectively. |
| M42675 | CHBO4 | CHBO4 is a potent, reversible, competitive, and selective hMAO-B inhibitor with an IC50 value of 0.031 μM in CHBO subseries and an Ki value of 0.010 ± 0.005 μM. |
| M42674 | hAChE-IN-3 | hAChE-IN-3 is a potent and blood-brain barrier permeable AChE, BuChE, MAO-B-IN-1 and BACE-1 inhibitor, with IC50 values of 0.44, 0.08, 5.15 and 0.38 μM, respectively. |
| M39204 | Echitovenidine | Echitovenidine is an alkaloid that can be isolated from Alstonia yunnanensis. Echitovenidine is an inhibitor of monoamine oxidase (MAO). |
| M39203 | Hydroxyamine hydrochloride | Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxyamine hydrochloride is an intermediate of organic synthesis. |
| M31063 | PXS-5153A monohydrochloride | PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. |
| M30381 | Bifemelane hydrochloride | Bifemelane hydrochloride (MCI-2016) is a potent, selective and competitive inhibitor of monoamine oxidase A (MAO-A), with a Ki of 4.20 μM. Bifemelane hydrochloride also inhibits MAO-B noncompetitively with a Ki of 46.0 μM. Bifemelane hydrochloride has a potent antidepressant activity and can be used for the research of cognitive and emotional disturbances related to cerebrovascular disease. |
| M30356 | Pirlindole | Pirlindole is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3). |
| M29619 | LOX-IN-3 dihydrochloride monohydrate | LOX-IN-3 dihydrochloride monohydrate (Compound 33) is an orally active lysyl oxidase (LOX) inhibitor. LOX-IN-3 dihydrochloride monohydrate can be used for fibrosis, cancer and angiogenesis research. |
| M29273 | CCT365623 hydrochloride | CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties. |
| M29203 | Ladostigil hemitartrate | Ladostigil (TV-3326) hemitartrate is an orally active dual inhibitor of cholinesterase and brain-selective monoamine oxidase (MAO), with IC50s of 37.1 and 31.8 μM for MAO-B and AChE, respectively. Ladostigil hemitartrate exhibits neuroprotective, antioxidant and anti-inflammatory activities. Ladostigil hemitartrate can be used for the research of depression and Alzheimer's disease. |
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