Free shipping on all orders over $ 500

HSP Heat shock proteins

Cat.No.  Name Information
M9899 Arimoclomol maleate Arimoclomol maleate (also known as BRX-220) is a heat shock protein amplifier, and is potentially useful for the treatment of Niemann-Pick disease type C (NP-C).
M9273 HSP70-IN-1 HSP70-IN-1 is a heat shock protein (HSP) inhibitor with an IC50 of 2.3 μM inhibiting the growth of Kasumi-1 cells.
M7575 Apoptozole Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively, and can induce apoptosis.
M1798 NVP-HSP990 NVP-HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.
M1741 Ganetespib Ganetespib (STA-9090) is a potent synthetic small molecule inhibitor of Hsp90 with potential antineoplastic activity.
M1725 CUDC-305 CUDC-305 is a heat shock protein 90 (HSP90) inhibitor of the novel imidazopyridine class.
M29916 Col003  Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen binding site on Hsp47 (IC50=1.8 μM). Col003 discourages the interaction of Hsp47 with collagen and inhibits collagen secretion by destabilizing the collagen triple helix. Col003 can be used for the investigation of fibrosis[1]
M20676 Pimitespib TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L).
M18398 Falcarinol Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor. Falcarinol (Panaxynol) induces apoptosis.
M13683 ML346 ML346 is an activator of Hsp70 expression and HSF-1 activity, with an EC50 of 4.6 μM for Hsp70.
M13680 Gamitrinib TPP hexafluorophosphate Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
M13679 CCT251236 CCT251236 is an orally available pirin ligand from a heat shock transcription factor 1 (hsf1) phenotypic screen with an IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction.
M11446 NPX800 NPX800 is an oral HSF1 inhibitor of FIC. NPX800 has the potential to be used in cancer research.
M10658 Calenduloside E Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata. Calenduloside E (CE) has anti-apoptotic potent by targeting heat shock protein 90 (Hsp90).
M10496 HM03 HM03 is a potent and selective HSPA5 inhibitor with anticancer activity.
M10289 Cucurbitacin D Cucurbitacin D induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.
M9846 JG-98 JG-98 is an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction.
M9304 KNK437 KNK437 is a specific heat shock protein (HSPA1A) inhibitor.
M9299 HSF1A HSF1A is an activator of Heat shock transcription factor 1 (HSF1).
M7427 TRC 051384 TRC 051384 is a inducer of heat shock protein Hsp70.

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.