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Arimoclomol citrate

Cat. No. M30000

All AbMole products are for research use only, cannot be used for human consumption.

Arimoclomol citrate Structure
Synonym:

BRX-220 citrate

Size Price Availability Quantity
5mg USD 90  USD90 In stock
10mg USD 150  USD150 In stock
25mg USD 300  USD300 In stock
50mg USD 520  USD520 In stock
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Quality Control & Documentation
Biological Activity

Arimoclomol citrate (BRX-220 citrate) is a co-inducer of heat shock proteins (HSP). Arimoclomol citrate protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.

Chemical Information
Molecular Weight 505.9
Formula C20H28ClN3O10
CAS Number 368860-21-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Cathrine K Fog, et al. EBioMedicine. The heat shock protein amplifier arimoclomol improves refolding, maturation and lysosomal activity of glucocerebrosidase

[2] Bernadett Kalmar, et al. Pharmacol Ther. The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol

[3] Julie Phukan. IDrugs. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis

[4] Zoltán Rakonczay Jr, et al. Free Radic Biol Med. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats

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Keywords: Arimoclomol citrate, BRX-220 citrate supplier, HSP, inhibitors, activators

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