About 17 results found for searched term "HSP" (0.054 seconds)
Cat.No. | Name | Target |
---|---|---|
M1798 | NVP-HSP990 | HSP |
HSP990 | ||
NVP-HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with IC50 values of 0.6, 0.8, and 8.5 nM for Hsp90α, Hsp90β, and Grp94, respectively. NVP-HSP990 has potential antineoplastic activity. | ||
M11299 | Recombinant Mouse HSP60 Protein (E.coli, His) | Cytokines and Growth Factors |
HSPD1 | ||
Recombinant Mouse HSP60 Protein (E.coli, His) is a member of the chaperone protein family. HSP60 acts as a signaling molecule in the innate immune system. | ||
M9273 | HSP70-IN-1 | HSP |
HSP70-IN-1 is a heat shock protein (HSP) inhibitor with an IC50 of 2.3 μM inhibiting the growth of Kasumi-1 cells. | ||
M13682 | HSP27 inhibitor J2 | HSP |
HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. | ||
M21707 | Recombinant Mouse HSP70 Protein (HEK293, His Tag) | Cytokines and Growth Factors |
HSPA1A; heat shock 70kDa protein 1A | ||
HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. The Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. | ||
M25207 | Verpasep caltespen | Others |
HspE7 | ||
Verpasep caltespen (HspE7) is a recombinant fusion protein derived from Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65), the C-terminal end of which is covalently linked to the E7 protein of HPV16. Verpasep caltespen can be used in the study of precancerous and cancerous lesions caused by human papillomavirus (HPV) . | ||
M28403 | HSP70-IN-4 | HSP |
HSP70-IN-4 (Compound YM-01) is an Hsp70 inhibitor with an IC50 of 3.2 μM. HSP70-IN-4 is not BBB permeable. | ||
M29822 | Aha1/Hsp90-IN-1 | Microtubule |
Aha1/Hsp90-IN-1 (Compound 17) is an Aha1/Hsp90 complex inhibitor. Aha1/Hsp90-IN-1 disrupts Aha1/Hsp90 interactions with an IC50 of 3.32 μM. Aha1/Hsp90-IN-1 inhibits tau aggregation. | ||
M31380 | Recombinant Human HSP70 Protein (HEK293, N-His) | Cytokines and Growth Factors |
HSP70-2; HSP72; HSPA1 | ||
HSP70 can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells. | ||
M41214 | HSP90-IN-21 | Parasite |
HSP90-IN-21 (5e) is an antiplasmodial agent, with IC50 values of 0.04, 0.17 and 2.91 μM against erythrocytic stage of P. | ||
M41508 | HSP90-IN-22 | HSP |
HSP90-IN-22 is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively. | ||
M41511 | HSP90-IN-23 | HSP |
HSP90-IN-23 is an inhibitor of heat shock protein 90(HSP90) with an IC50 of 9 nM. | ||
M41514 | HSP90-IN-20 | HSP |
HSP90-IN-20 is a potent HSP90 inhibitor with an IC50 of ≤10 μM. | ||
M42676 | MAO A/HSP90-IN-1 | Monoamine Oxidase |
MAO A/HSP90-IN-1 is a MAO A/HSP90 dual inhibitor with IC50 value of 1.77 μM and 0.019 μM in Glioblastoma (GBM) GL26 cells and HSP90α, respectively. | ||
M42678 | MAO A/HSP90-IN-2 | Monoamine Oxidase |
MAO A/HSP90-IN-2 is a dual inhibitor of HSP90and MAO A with the IC50 values of 0.016 and 4.58 μM, respectively. | ||
M43415 | PROTAC Hsp90α degrader 1 | HSP |
PROTAC Hsp90α degrader 1 is a selective PROTAC Hsp90α degrader. | ||
M54514 | Hsp70-derived octapeptide | HSP |
Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs. |
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