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Recombinant Mouse HSP60 Protein (E.coli, His)

Cat. No. M11299

All AbMole products are for research use only, cannot be used for human consumption.

Recombinant Mouse HSP60 Protein (E.coli, His) Structure
Synonym:

HSPD1

Size Price Availability Quantity
100ug USD 880  USD880 In stock
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Quality Control & Documentation
  • Purity: >75%, Endotoxin <1 EU/μg
  • COA
  • MSDS
Biological Activity

Recombinant Mouse HSP60 Protein (E.coli, His) is a member of the chaperone protein family. HSP60 acts as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. It may also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

A DNA sequence encoding the mouse HSP60 (NP_034607.3) (Leu 2-Phe 573) was expressed, with a polyhistide tag at the N-terminus.

The recombinant mouse HSP60 consisting of 583 amino acids and has a calculated molecular mass of 62.3 kDa. rmHSP60 migrates as an approximately 58 kDa band in SDS-PAGE under reducing conditions.

Lyophilized from sterile PBS, pH 7.4.

Chemical Information
Solubility (25°C) It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
Storage Stable for up to twelve months from date of receipt at -20℃ to -80℃
References

[1] Deling Zhang, et al. Cell Commun Signal. Heat shock protein 60 (HSP60) modulates adiponectin signaling by stabilizing adiponectin receptor

[2] Yaoyun Duan, et al. Cell Death Dis. Heat shock protein 60 regulates yolk sac erythropoiesis in mice

[3] Nan-Hee Seo, et al. Exp Mol Med. HSP60 is required for stemness and proper differentiation of mouse embryonic stem cells

[4] Tsung-Hsien Chen, et al. Biomed Res Int. Neonatal Death and Heart Failure in Mouse with Transgenic HSP60 Expression

[5] J P Heiserman, et al. Cell Stress Chaperones. TLR4 mutation and HSP60-induced cell death in adult mouse cardiac myocytes

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Keywords: Recombinant Mouse HSP60 Protein (E.coli, His), HSPD1 supplier, Cytokines and Growth Factors, inhibitors, activators

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