| Cat.No. | Name | Information |
|---|---|---|
| M55684 | GLP-1R agonist | GLP-1R agonist is a potent GLP-1R (glucagon-like peptide 1 receptor) agonist, with KB of 26.3 nM for the recombinant human receptor. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight. |
| M49466 | Retatrutide | Retatrutide is a triple agonist peptide for glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) that binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. Retatrutide can be used in studies related to obesity. |
| M41833 | Survodutide acetate | Survodutide (BI 456906) acetate is an glucagon and glucagon-like peptide 1 (GLP-1) receptor agonist Survodutide (TFA) is equivalent to Survodutide. |
| M41827 | Mazdutide | Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. |
| M31215 | Cotadutide | Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D). |
| M31106 | Survodutide | Survodutide is a dual agonist of the glucagon receptor and GLP-1 receptor and may be used in obesity-related studies. |
| M31094 | Retatrutide acetate | Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits for human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. |
| M25470 | Mazdutide acetate | Mazdutide (IBI362, LY3305677) is a novel glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. It can be used in studies of obesity and type 2 diabetes (T2D). |
| M13971 | MK 0893 | MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM. |
| M13966 | Adomeglivant | Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus. |
| M10914 | Dasiglucagon acetate | Dasiglucagon (Zegalogue) acetate is a Glucagon Receptor Agonist. The physiologic effect of dasiglucagon is by means of Increased Glycogenolysis. |
| M10144 | NNC0640 | NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM. |
| M9312 | Glucagon (1-29), bovine, human, porcine | Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation. |
| M8940 | GRA Ex-25 | GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively. |
| M8113 | PF-06291874 | PF-06291874 is an orally active, potent and selective glucagon receptor antagonist. |
| M54463 | Glucagon (19-29), human | Glucagon (19-29), human is a potent and efficient inhibitor of insulin secretion. |
| M54456 | Exendin-3/4 (59-86) | Exendin-3/4 (59-86) is a Exendin-4 peptide derivative. |
| M54433 | HAEGTFTSDVS | HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. |
| M54410 | GLP-1(32-36)amide | GLP-1(32-36)amide, a pentapeptide, derived from the C terminus of the glucoregulatory hormone GLP-1. |
| M54400 | HAEGTFTSD | HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide. |
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