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GLP-1R agonist is a potent GLP-1R (glucagon-like peptide 1 receptor) agonist, with KB of 26.3 nM for the recombinant human receptor. GLP-1 receptor signaling is a predominant mechanism for regulating glucose homeostasis. This compound represents a unique non-peptide tool for studying the role of GLP-1 in both in vivo and in vitro diabetes and obesity models.
| Molecular Weight | 348.25 |
| Formula | C13H15Cl2N3O2S |
| CAS Number | 281209-71-0 |
| Solubility (25°C) | DMSO 17 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Glucagon Receptor Products |
|---|
| Glucagon (19-29), human
Glucagon (19-29), human is a potent and efficient inhibitor of insulin secretion. |
| Exendin-3/4 (59-86)
Exendin-3/4 (59-86) is a Exendin-4 peptide derivative. |
| HAEGTFTSDVS
HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide. |
| GLP-1(32-36)amide
GLP-1(32-36)amide, a pentapeptide, derived from the C terminus of the glucoregulatory hormone GLP-1. |
| HAEGTFTSD
HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide. |
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