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Glucagon Receptor Glucagon Receptor

Inhibitors

Cat.No.  Name Information
M13972 Semaglutide TFA Semaglutide TFA, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.
M13971 MK 0893 MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM.
M13970 Lixisenatide acetate Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM).
M13968 GLP-1(7-36), amide acetate GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
M13967 GLP-1(7-37) acetate GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion.
M13966 Adomeglivant Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.
M11428 LSN3318839 LSN3318839 is an orally active allosteric modulator of glucagon-like peptide-1 receptor (GLP-1R).
M11319 GLP-1(7-36), amide TFA TFA is a major intestinal hormone that stimulates insulin secretion by pancreatic beta cells in response to glucose.
M11207 GLP-1(7-37) Glp-1 (7-37) is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
M10311 PF-06882961 PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor (GLP-1R) agonist.
M10249 Teduglutide Teduglutide is a glucagon-like peptide-2 (GLP- 2) receptor agonist used for the treatment of short-bowel syndrome.
M10144 NNC0640 NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM.
M10089 Avexitide (Exendin 9-39) Avexitide (Exendin 9-39) is a specific and competitive GLP-1 receptor antagonist.
M9749 Cotadutide acetate Cotadutide acetate is a potent peptide dual agonist of glucagon-like peptide-1 (GLP-1) and glucagon receptor, with EC50 values of 6.9 pM and 10.2 pM, respectively.
M9488 Tirzepatide TFA Tirzepatide (LY3298176) TFA is a first-in-class glucose-dependent insulin stimulating polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) agonist for diabetes research.
M9487 Tirzepatide hydrochloride Tirzepatide Hydrochloride is a first-in-class glucose-dependent insulin-stimulating peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist for the study of diabetes mellitus.
M9312 Glucagon Glucagon is a peptide hormone that helps regulate the blood sugar (glucose) levels in the body.
M9311 Liraglutide Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist.
M8940 GRA Ex-25 GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively.
M8113 PF-06291874 PF-06291874 is an orally active, potent and selective glucagon receptor antagonist.



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