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Glucagon Receptor Glucagon Receptor

Cat.No.  Name Information
M49466 Retatrutide Retatrutide is a triple agonist peptide for glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) that binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. Retatrutide can be used in studies related to obesity.
M41833 Survodutide acetate Survodutide (BI 456906) acetate is an glucagon and glucagon-like peptide 1 (GLP-1) receptor agonist Survodutide (TFA) is equivalent to Survodutide.
M41827 Mazdutide Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog.
M31106 Survodutide Survodutide is a dual agonist of the glucagon receptor and GLP-1 receptor and may be used in obesity-related studies.
M31094 Retatrutide acetate Retatrutide (LY3437943) acetate is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide acetate inhibits for human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively.
M25470 Mazdutide acetate Mazdutide (IBI362, LY3305677) is a novel glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist. It can be used in studies of obesity and type 2 diabetes (T2D).
M13971 MK 0893 MK 0893 is a potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM.
M13966 Adomeglivant Adomeglivant (LY2409021) is a potent, selective glucagon receptor (GluR) allosteric antagonist. Adomeglivant is widely used in the research for type 2 diabetes mellitus.
M10914 Dasiglucagon acetate Dasiglucagon (Zegalogue) acetate is a Glucagon Receptor Agonist. The physiologic effect of dasiglucagon is by means of Increased Glycogenolysis.
M10144 NNC0640 NNC0640 is a potent, negative allosteric modulator (NAM) of human G-protein-coupled glucagon receptor (GCGR) with IC50 of 69.2 nM.
M9312 Glucagon (1-29), bovine, human, porcine Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation.
M8940 GRA Ex-25 GRA Ex-25 is an inhibitor of glucagon receptor, with IC50 values of 56 and 55 nM for rat and human glucagon receptors, respectively.
M8113 PF-06291874 PF-06291874 is an orally active, potent and selective glucagon receptor antagonist.
M54463 Glucagon (19-29), human Glucagon (19-29), human is a potent and efficient inhibitor of insulin secretion.
M54456 Exendin-3/4 (59-86) Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.
M54433 HAEGTFTSDVS HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.
M54410 GLP-1(32-36)amide GLP-1(32-36)amide, a pentapeptide, derived from the C terminus of the glucoregulatory hormone GLP-1.
M54400 HAEGTFTSD HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide.
M54335 GLP-1(28-36)amide GLP-1(28-36)amide, a C-terminal nonapeptide of GLP-1, is a major product derived from the cleavage of GLP-1 by the neutral endopeptidase (NEP).
M54261 Bay 55-9837 Bay 55-9837 is a potent and highly selective agonist of VPAC2, with a Kd of 0.65 nM.

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