| Cat.No. | Name | Information |
|---|---|---|
| M10096 | GLPG0974 | GLPG0974 is a potent and selective free fatty acid receptor-2 (FFA2/GPR43) antagonist, with an IC50 of 9 nM. |
| M10746 | Denifanstat | Denifanstat (TVB-2640) is an orally potent selective FASN inhibitor.IC50 to 0.052 μM,EC50 is 0.072 μM. Denifanstat has the potential to be used in fatty liver and cancer research. |
| M3996 | Betulin | Betulin is a specific, small molecule inhibitor of SREBP (Sterol Regulatory Element-Binding Proteins). |
| M3549 | Orlistat | Orlistat is an irreversible inhibitor of pancreatic and gastric lipases with IC50 of 122 ng/ml for PL from human duodenal juice. |
| M2604 | C75 | C75 is a novel, potent synthetic inhibitor of fatty acid synthase (FAS). C75 inhibits prostate cancer cells PC3 with an IC50 of 35 μM. C75 is a potent CPT1A activator. |
| M56691 | Fasnall | Fasnall is a selective fatty acid synthase (FASN) inhibitor with an IC50 of 3.71 μM. |
| M56690 | Fasnall benzenesulfonate | Fasnall benzenesulfonate is the benzenesulfonate salt form of Fasnall. |
| M28252 | GSK837149A | GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer. |
| M20994 | Eicosapentaenoic acid ethyl ester | Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels. |
| M14433 | FASN-IN-1 | FASN-IN-1 is a fatty acid synthase (FASN) inhibitor. |
| M14432 | FASN-IN-4 tosylate | FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. |
| M13961 | GW-1100 | GW-1100 is a selective GPR40 antagonist with a pIC50 of 6.9. |
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