| Cat.No. | Name | Information |
|---|---|---|
| M28252 | GSK837149A | GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer. |
| M20994 | Eicosapentaenoic acid ethyl ester | Eicosapentaenoic acid ethyl ester (AMR101, EPA ethyl ester, Ethyl eicosapentaenoate) is an omega-3 fatty acid agent that significantly reduces the triglyceride (TG) levels and improves other lipid parameters without significantly increasing the low-density lipoprotein (LDL) cholesterol levels. |
| M20690 | FT113 | FT113 is a potent inhibitor of fatty acid synthase(FASN) with ic50 of 213 nM. |
| M14433 | FASN-IN-1 | FASN-IN-1 is a fatty acid synthase (FASN) inhibitor. |
| M14432 | FASN-IN-4 tosylate | FASN-IN-4 tosylate is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 tosylate also inhibits SARS-CoV-2 with an EC50 of 18.6 nM. |
| M14431 | Desoxyrhaponticin | Desoxyrhaponticin is a stilbene glycoside from the Tibetan nutritional food Rheum tanguticum Maxim. Desoxyrhaponticin is a Fatty acid synthase (FASN) inhibitor, and has apoptotic effect on human cancer cells. |
| M14430 | BI 99179 | BI 99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM. |
| M13961 | GW-1100 | GW-1100 is a selective GPR40 antagonist with a pIC50 of 6.9. |
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