| Cat.No. | Name | Information |
|---|---|---|
| M2084 | SCH772984 | SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. |
| M5158 | Tauroursodeoxycholic acid (Ursodoxicoltaurine) | Tauroursodeoxycholic acid (Ursodoxicoltaurine) is an endoplasmic reticulum stress inhibitor. It can significantly reduce the expression of apoptotic molecules such as caspase-3 and caspase-12. Tauroursodeoxycholate also suppresses ERK. It is a taurine conjugate of usodeoxycholic acid. |
| M4037 | Astragaloside IV | Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. |
| M49702 | ERK1/2 inhibitor 4 | ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. |
| M49701 | ERK1/2 inhibitor 3 | ERK1/2 inhibitor 3 is a potent inhibitor of ERK1/2. |
| M49700 | Enniatin A1 | Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids. |
| M49699 | Edaxeterkib | Edaxeterkib is a potent extracellular signal-regulated kinase (ERK) inhibitor for the research of cancer. |
| M49698 | DCZ19931 | DCZ19931 is a potent multi-targeting kinase inhibitor. |
| M49697 | Anti-inflammatory agent 31 | Anti-inflammatory agent 31 (enone 17) is a kind of andrographolide derivatives, is a anti-inflammatory agent. |
| M49696 | ADTL-EI1712 | ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 μM are 93.54% and 89.35%, respectively. |
| M49694 | 6-O-Isobutyrylbritannilactone | 6-O-Isobutyrylbritannilactone is a natural melanogenesis inhibitor. |
| M49693 | ERK-IN-4 | ERK-IN-4 is an ERK inhibitor binds preferentially to ERK2 with a Kd of 5 μM. |
| M49692 | ERK1/2 inhibitor 7 | ERK1/2 inhibitor 7 is a potent ERK inhibitor with an IC50 of 0.94 nM for ERK2. |
| M49691 | β-Neo-Endorphin | β-Neo-Endorphin is an endogenous opioid peptide. |
| M43554 | MEK-IN-6 | MEK-IN-6 is a MEK inhibitor. |
| M42121 | ERKtide | ERKtide is a biological active peptide. |
| M42120 | MHJ-627 | MHJ-627 is a potent ERK5 (MAPK7) inhibitor (IC50: 0.91 μM). |
| M42119 | ERK1/2 inhibitor 9 | ERK1/2 inhibitor 9 (Probe 1) is a covalent ERK1/2 inhibitor. |
| M42118 | Prolylserine | Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. |
| M42117 | KRAS G12C inhibitor 61 | KRAS G12C inhibitor 61 inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. |
| M42116 | ERK-IN-7 | ERK-IN-7, an analogue of SHR2415, is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively. |
| M39014 | Gardenin A | Gardenin A is an orally active and synthetic PMF analogue with the neurotrophic effect for neurite outgrowth and neuronal differentiation. Gardenin A promotes neuritogenesis via activating MAPK/ERK, PKC, and PKA, but not TrkA, CREB signaling pathways. |
| M39012 | Withanolide B | Withanolide B is an active component of W. somnifera Dunal. Withanolide B promotes osteogenic differentiation of hBMSCs via ERK1/2 and Wnt/β-catenin signaling pathways. Withanolide B exhibits neuroprotective, anti-arthritic, anti-aging and anti-cancer effects. |
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