| Cat.No. | Name | Information |
|---|---|---|
| M2084 | SCH772984 | SCH772984 is a novel and selective inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively. |
| M5158 | Tauroursodeoxycholic acid (Ursodoxicoltaurine) | Tauroursodeoxycholic acid (Ursodoxicoltaurine) is an endoplasmic reticulum stress inhibitor. It can significantly reduce the expression of apoptotic molecules such as caspase-3 and caspase-12. Tauroursodeoxycholate also suppresses ERK. It is a taurine conjugate of usodeoxycholic acid. |
| M4037 | Astragaloside IV | Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine. It has various effect on the cardiovascular, immune, digestive, and nervous systems. |
| M49723 | ZINC12409120 | ZINC12409120 is a high selective ERK inhibitor. |
| M49722 | Tizaterkib (hexanedioic acid) | Tizaterkib hexanedioic acid is a potent and selective ERK2 inhibitor, with an IC50 of 0.6 nM. |
| M49721 | TAT-MEK1 | TAT-MEK1 is an inhibitor ofERK2, consisting of TAT and MEK1 (N-terminal), TAT (YGRKKRRQRRR) derived from human immunodeficiency (HIV-1) transcriptional trans activator (TAT), is a cell-penetrating peptide. |
| M49720 | STE-MEK1(13) | STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH?) is a cell permeable ERK1/2 inhibitor (IC50: 13-30?μM). |
| M49719 | SHR2415 | SHR2415 is a highly potent, selective and orally active ERK1/2 inhibitor. |
| M49718 | Myristoyl-MEK1 Derived Peptide Inhibitor 1 | Myristoyl-MEK1 Derived Peptide Inhibitor 1 is the myristoylated form of the MEK1 Derived Peptide Inhibitor 1. |
| M49717 | mSIRK | mSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. |
| M49716 | MK2-IN-5 | MK2-IN-5 is a Mk2 pseudosubstrate (Ki= 8 μM). |
| M49714 | MEK1 Derived Peptide Inhibitor 1 | MEK1 Derived Peptide Inhibitor 1 is a peptide inhibitor. |
| M49713 | Laxiflorin B-4 | Laxiflorin B-4 is modificative compound of Laxiflorin B, exhibited higher affinity for ERK1/2 and stronger tumor suppression. |
| M49712 | Laxiflorin B | Laxiflorin B, a herbal compound, is a novel selective ERK1/2 inhibitor that has antitumor activity. |
| M49711 | ERK5-IN-6 | ERK5-IN-6 is an ERK5 kinase inhibitor with anticancer activity. |
| M49710 | ERK5-IN-5 | ERK5-IN-5 is an ERK5 kinase inhibitor with anticancer activity. |
| M49709 | ERK5-IN-4 | ERK5-IN-4 is a potent and selective inhibitor of extracellular signal-related kinase 5 (ERK5). |
| M49708 | ERK5-IN-3 | ERK5-IN-3 is a potent and selective ERK5 (extracellular signal-related kinase 5) inhibitor, with an IC50 of 6 nM. |
| M49707 | ERK2-IN-3 | ERK2-IN-3 is a inhibitor of ERK2, and inhibits Erk2WT and Erk2DS1 activation loop phosphorylation, with IC50 of 5 μM and 42 nM, respectively. |
| M49706 | ERK2 IN-1 | ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM. |
| M49705 | ERK1/2 inhibitor 8 | ERK1/2 inhibitor 8 is a potent ERK inhibitor with an IC50 of 0.48 nM for ERK2. |
| M49704 | ERK1/2 inhibitor 6 | ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2. |
| M49703 | ERK1/2 inhibitor 5 | ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2. |
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