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Metabolite/Endogenous Metabolite Metabolite/Endogenous Metabolite

Inhibitor

Cat.No.  Name Information
M10346 Glutamic acid (L-Glutamic acid) L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
M18309 p-Hydroxy-cinnamic acid p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
M6687 Docosahexaenoic acid (Oil) Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist.
M9953 Taurocholic acid Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats.
M10168 L-Lactic acid L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.
M22418 Calcium phosphorylcholine chloride Calcium phosphorylcholine chloride
M22061 Coproporphyrin III Coproporphyrin III
M21951 Biliverdin hydrochloride Biliverdin hydrochloride is a tetrapyrrolic, water-soluble compound formed by the breakdown of heme. Biliverdin hydrochloride can upregulate the activity of biliverdin reductase which is an enzyme that is a regulator of the innate immune system.
M21702 22(R)-Hydroxycholesterol 22(R)-Hydroxycholesterol is an intermediate of the pregnenolone synthesis pathway from cholesterol. It has neuroprotective properties and protects the neurons against β-amyloid-induced cell death.
M21637 Deltamethrin Deltamethrin produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.
M21636 Adenosine 5′-triphosphate magnesium salt Adenosine 5′-triphosphate magnesium salt is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division.
M21635 Phosphocreatine Phosphocreatine, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction
M21616 Cytidine-5'-monophospho-N-acetylneuraminic acid Cytidine-5'-monophospho-N-acetylneuraminic acid is a nucleotide.
M21614 2'3'-cGAMP 2'3'-cGAMP (2'-3'-cyclic GMP-AMP) is a endogenous cGAMP in mammalian cells. 2'3'-cGAMP binds to STING with a high affinity and is a potent inducer of interferon-β (IFNβ). 2'3'-cGAMP is produced in mammalian cells in response to DNA in the cytoplasm.
M21596 Pseudouridine Pseudouridine, an isomer of uridine, is also the most abundant modified nucleoside in non-coding RNA. Pseudouridine can fine-tune and stabilize the regional structure in rRNA and tRNA to maintain their function in mRNA decoding, ribosome assembly, processing, and translation.
M21529 All-trans-retinal All-trans-retinal is one of the major vitamin A metabolites in the retina. It is converted into retinoic acid in the body by retinal dehydrogenase. It is an effective photosensitizer.*The compound is unstable in solutions, freshly prepared is recommended
M21460 Cinnamoylglycine Cinnamoylglycine is a human urine metabolite, a glycine conjugate of cinnamic acid and. Cinnamoylglycine is used as a urine marker, which can be used as a marker for colonization of drug resistance after the antibiotic study period.
M21357 Ompenaclid Ompenaclid (RGX-202-01) is an orally active inhibitor of SLC6A8 transport protein. Ompenaclid (RGX-202-01) strongly inhibits creatine import in vitro and in vivo, decreases intracellular phosphocreatine and ATP levels, and induces apoptosis. Ompenaclid (RGX-202-01) has been used in oncology and Duchenne muscular dystrophy studies.
M21341 β-Muricholic Acid β-Muricholic acid is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.
M21340 α-Muricholic acid Alpha-Muricholic acid is one of the most abundant bile acids in rodents.
M21337 L-Dihydroorotic acid L-dihydroorotic acid (L-dihydroorotate) is an intermediate product of pyrimidine metabolism that can be reversibly hydrolyzed by dihydroorotase to yield acyclic L-ureidosuccinic acid.
M21265 Eicosapentaenoic Acid Eicosapentaenoic acid (EPA) is an omega-3 fatty acid found in fish oil. It acts as a precursor to prostaglandin-3 and thromboxane-3 families. EPA decreases serum lipid concentration, reduces the risk of cardiovascular disorders and suppresses platelet aggregation.Nutritional supplement in health care products.
M21129 Phosphoribosyl pyrophosphate pentasodium Phosphoribosyl pyrophosphate (PRPP) pentasodium is an important metabolite required for the biosynthesis of purine and pyrimidine nucleotides, the amino acids histidine and tryptophan, and the cofactors NAD and NADP.
M21086 Indole-3-pyruvic acid Indole-3-pyruvic acid, a ketone analogue of tryptophan, is an orally active AHR agonist. indole-3-pyruvic acid has antioxidant properties and can be used in studies of inflammation, anxiety.
M20950 N-Acetylglucosamine N-Acetylglucosamine is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. It may be helpful for the treatment of autoimmune diseases.




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