Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M10346 | Glutamic acid (L-Glutamic acid) | L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| M18309 | p-Hydroxy-cinnamic acid | p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. |
| M6687 | Docosahexaenoic acid (Oil) | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist. |
| M9953 | Taurocholic acid | Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats. |
| M10168 | L-Lactic acid | L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. |
| M57281 | 3-Methyl-2-oxovaleric acid | 3-methyl-2-oxovaleric acid (KMV) is a 2-oxoglutarate dehydrogenase (OGDH) inhibitor. 3-Methyl-2-oxovaleric acid is also a neurotoxin, an acidogen, and a metabotoxin. 3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. |
| M57276 | Succinyl-Coenzyme A sodium | Succinyl-Coenzyme A (SCoA) sodium is an intermediate of the citric acid cycle. Succinyl-Coenzyme A sodium can be converted to succinic acid and can also combines with glycine to form δ-ALA to synthesize porphyrins (heme). Succinyl-Coenzyme A (SCoA) is also an inhibitor of TCA cycle. |
| M56679 | AFMK | AFMK, antioxidant metabolite of Melatonin, attenuates X-ray-induced oxidative damage to DNA, proteins and lipids in mice. |
| M56657 | 17a-Hydroxypregnenolone | 17a-Hydroxypregnenolone is a pregnane steroid. |
| M56623 | SN-38 glucuronide | SN-38 glucuronide is an inactive metabolite of the anticancer active molecule Irinotecan and has toxic effects on the gastrointestinal tract. |
| M55678 | Dapagliflozin-3-O-β-D-glucuronide | Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin, and is formed in the liver and kidney by uridine diphosphate glucuronosyltransferase-1A9 (UGT1A9). |
| M55553 | p-Cresyl sulfate potassium | p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity. p-Cresyl Sulfate is a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver. |
| M55550 | p-Cresyl sulfate | p-Cresyl Sulfate is a major uremic toxin derived from the metabolites of tyrosine and phenylalanine through liver. |
| M55532 | DL-Tryptophan-d5 | DL-Tryptophan-d5 |
| M55486 | Octanoic acid-d15 | Octanoic acid-d15 |
| M55484 | Pentanoic-d9 acid | Pentanoic-d9 acid |
| M55483 | Succinic acid-d6 | Succinic acid-d6 |
| M55431 | DL-Homocysteine-d4 | DL-Homocysteine-d4 |
| M55418 | Vitamin K1-d4 | Vitamin K1-d4 |
| M55416 | Vitamin K1-d7 | Vitamin K1-d7 |
| M55411 | N-Arachidonylglycine | N-Arachidonylglycine (NA-Gly) is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration. |
| M55407 | Cysteinylglycine | Cysteinylglycine is an endogenous metabolite. |
| M55383 | N-Methylnicotinamide | N-Methylnicotinamide (MNA, Nicotinyl Methylamide, N-Methyl-3-pyridinecarboxamide) is an active endogenous metabolite that improves endothelial dysfunction and attenuates atherosclerosis by modulating the ADMA-DDAH axis. |
| M55367 | 2-Naphthol | 2-Naphthol is a metabolite of naphthalene, catalyzed by cytochrome P450 (CYP) isozymes (CYP 1A1, CYP 1A2, CYP 2A1, CYP 2E1 and CYP 2F2). |
| M55352 | 3-Chloro-L-tyrosine | 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and it is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. |
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