Inhibitor
| Cat.No. | Name | Information |
|---|---|---|
| M10346 | Glutamic acid (L-Glutamic acid) | L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| M18309 | p-Hydroxy-cinnamic acid | p-Hydroxy-cinnamic acid inhibits platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively. |
| M6687 | Docosahexaenoic acid (Oil) | Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. Docosahexaenoic acid is a RXR agonist. |
| M9953 | Taurocholic acid | Taurocholic acid (N-Choloyltaurine) is a bile acid, which can be used in the emulsification of fats. |
| M10168 | L-Lactic acid | L-Lactic acid is an organic acid, which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. |
| M31283 | Glucose oxidase | Glucose oxidase (GOD) is an oxidoreductase enzyme that inhibits the proliferation of cancer cells by reacting with intracellular oxygen (O2) and β-D-glucose to produce hydrogen peroxide (H2O2) and gluconic acid, thereby cutting off the source of nutrients for cancer cells. |
| M9076 | NADPH tetrasodium salt | NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication. |
| M14386 | Maltol | Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food. |
| M58952 | Urolithin M7 | Urolithin M7 is a metabolite, which is derived from the transformation of ellagitannins, compounds found predominantly in pomegranates, berries, and nuts. This transformation occurs via intestinal microbiota, which convert ellagitannins into various urolithins, including Urolithin M7. Its mode of action involves influencing cellular processes, potentially modulating mitochondrial function and autophagy pathways. |
| M58946 | D-Glucose-13C6 | D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard. |
| M58714 | D-Alanine | D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR. |
| M58702 | Quercetin 7-glucuronide | Quercetin 7-glucuronide can inhibit LDL oxidation. Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide) can be isolated from Madagascarian Uncarina species. |
| M58690 | D-Tryptophan | D-Tryptophan is the D-isomer of tryptophan, as a non-protein active amino acid, has special physiological properties, can be used as additives, plant growth agents, etc. In the pharmaceutical industry, it is mainly used in the synthesis of various polypeptides, instead of L-tryptophan to extend the peptide half-life. |
| M58670 | Arachidonic acid sodium salt | Arachidonic acid sodium salt (Sodium Arachidonate) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). |
| M58650 | trans-Vaccenic acid | trans-Vaccenic acid is a naturally occurring trans fatty acid (TFA). trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated Linoleic acid (CLA) at the tissue level. trans-Vaccenic acid inhibits nasopharyngeal carcinoma (NPC) cell growth and induces apoptosis through the inhibition of Bad/Akt phosphorylation. |
| M58548 | p-Cresol glucuronide | p-Cresol glucuronide is a metabolite of p-cresol, it is a prototype protein-bound uremic toxin. |
| M58532 | Oleamide | Oleamide is an endogenous fatty acid amide. |
| M58531 | Deoxycarnitine chloride | Deoxycarnitine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota. |
| M58523 | Monobutyl phthalate | Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. |
| M58517 | 2'-Deoxyinosine | 2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability. |
| M58498 | SR-4995 | SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling. |
| M58460 | NAD sodium | NAD sodium (β-Nicotinamide adenine dinucleotide sodium salt) is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP. |
| M58419 | L-Leucyl-L-Leucine methyl ester hydrochloride | L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress. |
| M58395 | 8-Hydroxyguanosine | 8-Hydroxyguanosine is a marker compound indicative of DNA damage associated with mutagenesis and carcinogenesis. 8-Hydroxyguanosine is a purine nucleoside, it stimulates proliferation and differentiation of B cells. |
| M58391 | trans-Urocanic acid | trans-Urocanic acid is a natural epidermal constituent, which inhibits human natural killer cell (NK) activity in vitro. trans-Urocanic acid is active in regulating an immune function. |
| M58377 | Anserine | Anserine is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. |
| M58371 | ω-Muricholic Acid | ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid. |
| M58361 | N-acetyldopamine | N-acetyldopamine (NADA) is a catecholamine that is used by insects as sclerotizing precursors to harden their cuticle. |
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