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L-Homocitrulline

Cat. No. M45192

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L-Homocitrulline Structure
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100mg USD 36 In stock
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Quality Control & Documentation
Biological Activity

L-Homocitrulline is an amino acid that is also a metabolite of ornithine in mammalian metabolism.Abnormal metabolism of L-Homocitrulline leads to lysine urinary protein intolerance (LPI).

Chemical Information
Molecular Weight 189.21
Formula C7H15N3O3
CAS Number 1190-49-4
Form Solid
Solubility (25°C) Water 33.33 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xinyi Ding, et al. Atherosclerosis. l-thyroxine attenuates extracellular Hsp90α-induced vascular endothelial calcification in diabetes mellitus, as revealed by parallel metabolic profiles

[2] D F Evered, et al. Br J Nutr. Absorption of homocitrulline from the gastrointestinal tract

[3] R W Wilson, et al. Biochem Med. A new metabolic product of L-homocitrulline

[4] R W Wilson, et al. Biochem Pharmacol. Metabolism of L-homocitrulline by a mouse liver enzyme

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: L-Homocitrulline supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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