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Abmole Inhibitor Catalog 2017

Drug-Linker Conjugates for ADC Drug-Linker Conjugates for ADC

Inhibitors

Cat.No.  Name Information
M10408 SuO-Val-Cit-PAB-MMAE SuO-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB.
M10406 N3-PEG3-vc-PAB-MMAE N3-PEG3-vc-PAB-MMAE is a synthesized drug-linker conjugate for ADC that incorporates the MMAE (a tubulin inhibitor ) and 3-unit PEG linker.
M10405 Fmoc-Val-Cit-PAB-MMAE Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADCs that consists of a ADC linker (Fmoc-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE).
M10403 MC-Val-Cit-PAB-MMAF MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.
M10402 MC-GGFG-DX8951 MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker.
M10400 Val-Cit-PAB-MMAE Val-Cit-PAB-MMAE is a MMAE derivative with a cleavable linker, which is useful to make MMAE conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended
M10398 Mc-MMAE Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended
M10397 McMMAF McMMAF is a protective group-conjugated MMAF. *The compound is unstable in solutions, freshly prepared is recommended
M10396 Deruxtecan Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
M9750 Vipivotide tetraxetan Vipivotide tetraxetan (PSMA-617) is a potent prostate-specific membrane antigen (PSMA) inhibitor with Ki value of 0.37 nM, it is used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.


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