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Ladiratuzumab vedotin

Cat. No. M24756

All AbMole products are for research use only, cannot be used for human consumption.

Ladiratuzumab vedotin Structure
Synonym:

SGN-LIV1A

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Quality Control & Documentation
Biological Activity

Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC50: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer.

Chemical Information
CAS Number 1629760-29-7
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Rita De Sanctis, et al. Front Pharmacol. From seaside to bedside: Current evidence and future perspectives in the treatment of breast cancer using marine compounds

[2] Ana Isabel Fraguas-Sánchez, et al. Cancers (Basel). Actively Targeted Nanomedicines in Breast Cancer: From Pre-Clinal Investigation to Clinic

[3] Alessandro Rizzo, et al. Expert Opin Investig Drugs. Ladiratuzumab vedotin for metastatic triple negative cancer: preliminary results, key challenges, and clinical potential

[4] Julia E McGuinness, et al. Expert Opin Biol Ther. Antibody-drυg conjugates in metastatic triple negative breast cancer: a spotlight on sacituzumab govitecan, ladiratuzumab vedotin, and trastuzumab deruxtecan

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Abmole Inhibitor Catalog




Keywords: Ladiratuzumab vedotin, SGN-LIV1A supplier, Drug-Linker Conjugates for ADC, inhibitors, activators

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