| Cat.No. | Name | Information |
|---|---|---|
| M9872 | BS3 (bis(sulfosuccinimidyl)suberate) | BS3 (bis(sulfosuccinimidyl)suberate) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M10405 | Fmoc-Val-Cit-PAB-MMAE | Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADCs that consists of a ADC linker (Fmoc-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). |
| M10403 | MC-Val-Cit-PAB-MMAF | MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB. |
| M10402 | MC-GGFG-DX8951 | MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker. |
| M10400 | Val-Cit-PAB-MMAE | Val-Cit-PAB-MMAE is a MMAE derivative with a cleavable linker, which is useful to make MMAE conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended |
| M10398 | Mc-MMAE | Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a drug-linker conjugate for ADC. *The compound is unstable in solutions, freshly prepared is recommended |
| M10397 | McMMAF | McMMAF is a protective group-conjugated MMAF. *The compound is unstable in solutions, freshly prepared is recommended |
| M10396 | Deruxtecan | Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. |
| M10199 | DSS Crosslinker (Disuccinimidyl suberate) | DSS Crosslinker (Disuccinimidyl suberate) is a non-cleavable, cell membrane permeable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| M9879 | Sulfo-SMCC sodium | Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. |
| M9655 | CL2A-SN-38 | CL2A-SN-38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an ADC. |
| M9036 | DM1-SMCC | DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make ADC. |
| M5070 | Mc-Val-Cit-PABC-PNP | Mc-Val-Cit-PABC-PNP is a histone-cleavable peptide linker for antibody-drug couplings (ADCs) that can be used for the synthesis of ADCs such as Brentuximab vedotin. |
| M55738 | MC-SN38 | MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). |
| M55737 | DM4-SMCC | DM4-SMCC is a agent-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker. |
| M55736 | Lys-SMCC-DM1 | Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. |
| M55735 | Doxorubicin-SMCC | Doxorubicin-SMCC is a agent-linker conjugate for ADC. |
| M55734 | Mal-PEG4-VC-PAB-DMEA-PNU-159682 | Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. |
| M55733 | Mal-amido-PEG8-Val-Ala-PAB-SG3200 | Mal-amido-PEG8-Val-Ala-PAB-SG3200 is a conjugate for antibody-drug conjugate (ADC). |
| M49829 | SC-VC-PAB-MMAE | SC-VC-PAB-MMAE is part of a drug-linker conjugate for ADC (ADC) with anticancer activity, which consists of MMAE (a tubulin inhibitor) linked to a cleavable SC-VC-PAB linker. |
| M49827 | DBCO-(PEG)3-VC-PAB-MMAE | DBCO-(PEG)3-vc-PAB-MMAE is an active molecule coupler (drug-linker conjugate for ADC) consisting of auristatin E attached to a DBCO-(PEG)3-vc-PAB connector. It can be used for cancer research. In addition, DBCO-(PEG)3-vc-PAB-MMAE is a click chemistry that contains a DBCO moiety and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an Azide moiety. |
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